Results 91 to 100 of about 12,220,401 (374)

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

The GIBACHT fellowship: a multilateral initiative for strengthening capacity in biosafety and biosecurity towards pandemic preparedness

Frontiers in Public Health
The German Biosecurity Programme was launched in 2013 with the aim to support partner countries overcome biological threats including natural outbreaks or the intentional misuse of highly pathogenic agents. As part of this programme, this paper describes
Eva Mertens, Eva Mertens, Marlow Zimmermann, Marlow Zimmermann, Janine Dywicki, Janine Dywicki, Min-Hi Lee, Min-Hi Lee, Joachim Pelikan, Joachim Pelikan, Joachim Pelikan, Barbara M. Bürkin, Barbara M. Bürkin, Barbara M. Bürkin, Elizeus Rutebemberwa, Elizeus Rutebemberwa, Axel Hoffmann, Axel Hoffmann, Axel Hoffmann   +18 more
doaj   +1 more source

In vitro micropropagation of Stevia rebaudiana Bertoni in Malaysia

Brazilian Archives of Biology and Technology, 2014
Stevia rebaudiana Bertoni is a medicinal plants and commercially use as non-caloric sweetener for diabetic patient. In the present study, a protocol was developed for in vitro micropropagation using 6-benzylamino purine (BAP) and Kinetin (Kn) for the ...
Ummi Nur Ain Abdul Razak, Chong Boon Ong, Tiew Sing Yu, Li Kiaw Lau   +3 more
doaj   +1 more source

FAM46B suppresses proliferation, migration and invasion of non-small cell lung cancer via β-catenin/MMP7 signaling [PDF]

, 2019
Hongyang Sang, Song Wu, Xifang Chen, Shaofei Cheng, Qianping Li   +4 more
openalex   +1 more source

Long non-coding RNA LOC285194 inhibits proliferation and migration but promoted apoptosis in vascular smooth muscle cells via targeting miR-211/PUMA and TGF-β1/S100A4 signal [PDF]

, 2020
Shao‐Chun Wang, Ping Li, Gang Jiang, Jinping Guan, Dong Chen, Xiaoying Zhang   +5 more
openalex   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

The evolution of the U.S. nuclear non-proliferation policy in the 1970s

Journal of Human Environmental Studies, 2009
This paper examines (1) how the Ford Administration tried to persuade South Korea to give up obtaining the spent nuclear fuel reprocessing plant and their related technologies, which were one of the most sensitive among peaceful nuclear use, and (2) how ...
Shinsuke Tomotsugu
doaj   +1 more source

The Future of the Non-proliferation Treaty [PDF]

, 2018
Harald Müller
openalex   +1 more source

Dispositioning military plutonium to promote nuclear non-proliferation [PDF]

, 2005
Given that all chemical varieties of plutonium can be used in nuclear weapons, sophisticated measures are required to disposition it so that its potential to contribute to horizontal and vertical nuclear proliferation is minimised.
Sancton, Robert
core  

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source