Results 71 to 80 of about 12,076,128 (300)
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Investigation of nuclear material using a compact modified uniformly redundant array gamma camera
Nuclear Engineering and Technology, 2018 We developed a compact gamma camera based on a modified uniformly redundant array coded aperture to investigate the position of a UO2 pellet emitting characteristic X-rays (98.4 keV) and γ-rays (185.7 keV).
Taewoong Lee, Sung-Woo Kwak, Wonho Lee
doaj +1 more source
The global nuclear order and the crisis of the nuclear non-proliferation regime: Taking stock and moving forward. [PDF]
Z Friedens Konfliktforsch, 2021 Baldus J, Müller H, Wunderlich C.
europepmc +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
The European Union's Nuclear Non-proliferation Policy
This book looks at European Union (EU) attempts to manage the risks associated with nuclear non-proliferation and assesses its performance and external challenges.
Herrera, Manuel
core +1 more source
In vivo imaging of cellular proliferation in colorectal cancer using positron emission tomography [PDF]
, 2003 Background and aims: Positron emission tomography (PET) using 18F labelled 2-fluoro-2-deoxy-D-glucose (18FDG) is an established imaging tool, although the recent development of a biologically stable thymidine analogue [18F] 3'-deoxy-3-fluorothymidine ...
Costa, D.C. +7 more
core
The regulation of haemopoietic stem cell and progenitor cell proliferation by humoral factors [PDF]
, 2012 The mechanisms which regulate the growth fraction of the haemopoietic stem cell (CFU-S) and granulocyte macrophage progenitor cell (GM-CFC) have been investigated.
Cork, Michael John
core +2 more sources
The Treaty on the Prohibition of Nuclear Weapons: Strengths, Weaknesses and Current Status
Journal for Peace and Nuclear DisarmamentThis commentary offers an analysis of the Treaty on the Prohibition of Nuclear Weapons (TPNW), its strengths, weaknesses, relationship to other agreements as well as recent updates.
Jean Krasno, Elisabeth Szeli
doaj +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source