Results 51 to 60 of about 1,440,127 (285)
North Korea and the Non-proliferation Regime [PDF]
In this review of the implications of North Korea’s behaviour during 2009 on the Non-proliferation Regime, it is stressed that if North Korea cannot be deterred from its nuclear ambitions this will deliver a serious blow to the international non ...
Reiss, Mitchell B.
core +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Türkiye’s Nuclear Nonproliferation Policy: History and Prospects
The relevance of the topic lies in the increasing role of nuclear weapons in international relations, both as a political and military tool and as a means of exerting influence and engaging in confrontation.
Tatyana V. Kashirina +1 more
doaj +1 more source
Background Hepatocellular carcinoma (HCC) is a common cancer leading to high morbidity and mortality in worldwide. Previous studies revealed that SEC61 translocon alpha 1 subunit1 (SEC61A) can act as an oncogene in colon adenocarcinoma.
Xinxin Fa +4 more
doaj +1 more source
Dispositioning military plutonium to promote nuclear non-proliferation [PDF]
Given that all chemical varieties of plutonium can be used in nuclear weapons, sophisticated measures are required to disposition it so that its potential to contribute to horizontal and vertical nuclear proliferation is minimised.
Sancton, Robert
core
This Is Not a Myeloproliferative Neoplasm…
Pediatric Blood &Cancer, EarlyView.
Stephanie Juané Kennedy
wiley +1 more source
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
‘I think we cannot refuse the order’: Britain, America, nuclear non-proliferation, and the Indian Jaguar deal, 1974–1978 [PDF]
This article sheds light on the way in which British negotiations with India over the potential purchase of the Jaguar strike aircraft during the 1970s complicated global nuclear non-proliferation diplomacy.
Craig, MM
core +1 more source
Sherlock Holmes Meets Rube Goldberg: Fixing the Entry-into-Force Provisions of the Comprehensive Nuclear Test Ban Treaty [PDF]
The Comprehensive Nuclear Test Ban Treaty (CTBT) is widely heralded as the most important international legal instrument for arresting the nuclear arms race and impeding further nuclear proliferation.
Koplow, David A.
core +2 more sources

