Results 91 to 100 of about 12,076,128 (300)

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

World at Risk: The Report of the Commission on the Prevention of WMD Proliferation and Terrorism [PDF]

, 2008
This book outlines the findings of the bipartisan Commission on the Prevention of Weapons of Mass Destruction Proliferation and Terrorism, established to build on the work of the 9/11 Commission. The Commission's report examines the government's current
Commission on the Prevention of Weapons of Mass Destruction Proliferation and Terrorism (U.S.)
core  

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Assessing the Heat Transfer Modeling Capabilities of CFD Software for Involute-Shaped Plate Research Reactors

Energies
The ongoing efforts to convert High-Performance Research Reactors (HPRRs) using Highly Enriched Uranium (HEU) to Low-Enriched Uranium (LEU) fuel require reliable thermal–hydraulic assessments of modified core designs. The involute-shaped fuel plates used
Cezary Bojanowski, Ronja Schönecker, Katarzyna Borowiec, Kaltrina Shehu, Julius Mercz, Frederic Thomas, Yoann Calzavara, Aurelien Bergeron, Prashant Jain, Christian Reiter, Jeremy Licht   +10 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Nuclear states as a factor of destabilization of international security: theoretical discussion and conceptual analysis

Вісник Харківського національного університету імені В.Н. Каразіна: Серія Міжнародні відносини, економіка, країнознавство, туризм
This article explores the complex and multifaceted impact of nuclear-armed states on contemporary international security. Particular emphasis is placed on the destabilizing role of nuclear weapons, especially in the context of threats posed by nuclear ...
Hanna Panasenko, Juliana Dovbnya
doaj   +1 more source

Non-proliferation [PDF]

Nature, 1980
openaire   +2 more sources

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Transitioning from the Nuclear Non-Proliferation Regime to a Future Global Nuclear-Zero Regime: What Legal and Institutional Issues Will the TPNW Need to Address Going Forward?

Journal for Peace and Nuclear Disarmament
Achieving a world without nuclear weapons requires a transition from today’s nuclear non-proliferation regime to a durable nuclear-zero regime. Separating (i) legal and institutional functions of a legal framework from (ii) enabling conditions beyond ...
Michiru Nishida
doaj   +1 more source

UNVEILING DUALITIES: US RHETORIC AND REALITY IN GLOBAL NUCLEAR NON-PROLIFERATION UNDER TRUMP AND BIDEN ADMINISTRATIONS

Margalla Papers, 2023
The image the United States has always projected of itself in the international community is that of a state that is nuclear responsible and bears the responsibility to keep nuclear proliferation in check.
Asma Rashid , Aiman Saif Ullah
doaj