Results 51 to 60 of about 1,391,444 (333)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Civil society legitimacy and nuclear non-proliferation [PDF]
, 2008 During recent years, civil society legitimacy has generated a growing interest in scholarly research. The present article therefore proposes four normative criteria, namely, independence, transparency, participation, and inclusion, in order to start ...
Kissling, Claudia
core
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
United States Nuclear Export Controls [PDF]
, 1980 This article will explore the U.S. nuclear export controls regime. It will initially discuss controls affecting the export of nuclear material, facilities, and specially designed components of nuclear facilities.
Marshall, Jr., Harry R. +1 more
core +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Atlanta Consultation II: On the Future of the NPT [PDF]
, 2005 The Middle Powers Initiative, a program of the Global Security Institute, organized an Extraordinary Strategy Consultation on the Nuclear Non-proliferation Treaty (NPT) 2005 Review Conference in cooperation with former U.S.
core
Determining Reactor Neutrino Flux
, 2012 Flux is an important source of uncertainties for a reactor neutrino experiment. It is determined from thermal power measurements, reactor core simulation, and knowledge of neutrino spectra of fuel isotopes.
Cao, Jun
core +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
‘I think we cannot refuse the order’: Britain, America, nuclear non-proliferation, and the Indian Jaguar deal, 1974–1978 [PDF]
This article sheds light on the way in which British negotiations with India over the potential purchase of the Jaguar strike aircraft during the 1970s complicated global nuclear non-proliferation diplomacy.
Craig, MM
core +1 more source
Export Control Regulations in the United Arab Emirates - Comparative Analysis with the United Kingdom [PDF]
, 2019 Governments across the world appreciate the need for checks on the transfer or exportation of commodities, information, software, and technology considered of strategic value.
Malkawi, Bashar H.
core +1 more source