Results 81 to 90 of about 13,597,353 (325)

Nuclear disarmament and non proliferation a view to posible changes. [PDF]

open access: yes, 2012
This paper called “Nuclear Disarmament and Non Proliferation: A view to possible changes” is a result of a wide investigation about this relevant topic in the international scope.
Ante Levoyer, Felipe
core  

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

Australia and the Non-Proliferation and Disarmament Initiative: difficult times for disarmament diplomacy [PDF]

open access: yes
Australia recognises the critical role that the Treaty on the Non-Proliferation of Nuclear Weapons plays in preventing uncontrolled proliferation and promoting disarmament, and upholding the treaty has long been a core foreign policy goal.
Tanya Ogilvie-White
core  

EU Foreign Policy Identity: A Case Study on the EU’s Engagement of the Islamic Republic of Iran. College of Europe EU Diplomacy Paper 06/2019 [PDF]

open access: yes, 2019
The Joint Comprehensive Plan of Action (JCPOA) is often referred to as the biggest foreign policy success of the European Union (EU). It ended twelve years of tough negotiations, stabilising one of the most volatile regions of the world.
McCloskey-Gholikhany, Leah
core  

The Treaty on the Prohibition of Nuclear Weapons: Strengths, Weaknesses and Current Status

open access: yesJournal for Peace and Nuclear Disarmament
This commentary offers an analysis of the Treaty on the Prohibition of Nuclear Weapons (TPNW), its strengths, weaknesses, relationship to other agreements as well as recent updates.
Jean Krasno, Elisabeth Szeli
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Nuclear Imminence in Contemporary Indo‐Pakistani Conflict [PDF]

open access: yes, 2009
November of 2008 saw frightening attacks on India’s foreigners. Over the course of three days, hostages had been taken, hotels and restaurants in India’s busiest city of Mumbai were burned and English, American and Canadian citizens lay among the nearly ...
Tobin, Anna K.
core  

In vitro micropropagation of Stevia rebaudiana Bertoni in Malaysia

open access: yesBrazilian Archives of Biology and Technology, 2014
Stevia rebaudiana Bertoni is a medicinal plants and commercially use as non-caloric sweetener for diabetic patient. In the present study, a protocol was developed for in vitro micropropagation using 6-benzylamino purine (BAP) and Kinetin (Kn) for the ...
Ummi Nur Ain Abdul Razak   +3 more
doaj   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

open access: yesMolecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute   +17 more
wiley   +1 more source

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