Results 31 to 40 of about 335,095 (291)

A nonparametric test for comparing survival functions based on restricted distance correlation

open access: yesDependence Modeling, 2023
In this article, we propose an omnibus test for comparing two survival functions under non-proportional hazards. The test statistic is based on a product-limit estimate of the restricted distance correlation, which is closely related to the L2{L}_{2 ...
Zhang Qingyang
doaj   +1 more source

Time-dependent treatment effects of metronomic chemotherapy in unfit AML patients: a secondary analysis of a randomised controlled trial

open access: yesBMC Research Notes, 2021
Objectives To examine the presence of the time-dependent effect of metronomic chemotherapy for the treatment of older patients with acute myeloid leukemia (AML) who were unfit for standard chemotherapy and to reanalyze the data using an appropriate ...
Phichayut Phinyo   +2 more
doaj   +1 more source

Generating Survival Times to Simulate Cox Proportional Hazards Models [PDF]

open access: yes, 2003
This paper discusses techniques to generate survival times for simulation studies regarding Cox proportional hazards models. In linear regression models, the response variable is directly connected with the considered covariates, the regression ...
Augustin, Thomas   +2 more
core   +2 more sources

The Duration of New Job Matches in East and West Germany [PDF]

open access: yes, 2004
This study compares the duration of new job matches in the east and west German labour market that formed between the start of the German Economic, Monetary and Social Union in July 1990 and December 2000. The study relies on job duration data drawn from
Wolff, Joachim
core   +7 more sources

Oral diabetes medication monotherapy and short-term mortality in individuals with type 2 diabetes and coronary artery disease [PDF]

open access: yes, 2018
Objective To determine whether sulfonylurea use, compared with non-sulfonylurea oral diabetes medication use, was associated with 2-year mortality in individuals with well-controlled diabetes and coronary artery disease (CAD). Research design and methods
Berkowitz, Seth A   +7 more
core   +3 more sources

Testing proportional hazards for specified covariates

open access: yesModern Stochastics: Theory and Applications, 2019
Tests for proportional hazards assumption concerning specified covariates or groups of covariates are proposed. The class of alternatives is wide: log-hazard rates under different values of covariates may cross, approach, go away.
Vilijandas Bagdonavičius   +1 more
doaj   +1 more source

Analysis of time to event outcomes in randomized controlled trials by generalized additive models. [PDF]

open access: yesPLoS ONE, 2015
BACKGROUND:Randomized Controlled Trials almost invariably utilize the hazard ratio calculated with a Cox proportional hazard model as a treatment efficacy measure.
Christos Argyropoulos, Mark L Unruh
doaj   +1 more source

Are non-constant rates and non-proportional treatment effects accounted for in the design and analysis of randomised controlled trials? A review of current practice

open access: yesBMC Medical Research Methodology, 2019
Background Most clinical trials with time-to-event primary outcomes are designed assuming constant event rates and proportional hazards over time. Non-constant event rates and non-proportional hazards are seen increasingly frequently in trials.
Kim Jachno   +2 more
doaj   +1 more source

Weighted Cox Regression Using the R Package coxphw

open access: yesJournal of Statistical Software, 2018
Cox's regression model for the analysis of survival data relies on the proportional hazards assumption. However, this assumption is often violated in practice and as a consequence the average relative risk may be under- or overestimated.
Daniela Dunkler   +3 more
doaj   +1 more source

Time and dose dependency of bone-sarcomas in patients injected with radium-224 [PDF]

open access: yes, 1988
The time course and dose dependency of the incidence of bone-sarcomas among 900 German patients treated with high doses of radium-224 is analysed in terms of a proportional hazards model with a log-normal dependency of time to tumor and a linear ...
A. M. Kellerer   +14 more
core   +1 more source

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