Results 51 to 60 of about 10,758,008 (293)

A mixed model approach for structured hazard regression [PDF]

, 2004
The classical Cox proportional hazards model is a benchmark approach to analyze continuous survival times in the presence of covariate information. In a number of applications, there is a need to relax one or more of its inherent assumptions, such as ...
Thomas Kneib, Kneib, Thomas, Ludwig Fahrmeir, Fahrmeir, Ludwig, Denuit, Michel   +4 more
core   +1 more source

Robust frailty modelling using non-proportional hazards models [PDF]

Statistical Modelling, 2010
Correlated survival times can be modelled by introducing a random effect, or frailty component, into the hazard function. For multivariate survival data, we extend a non-proportional hazards (PH) model, the generalized time-dependent logistic survival model, to include random effects.
Do Ha, II, Mackenzie, Gilbert
openaire   +2 more sources

Early Body Mass Index z‐Score Change and Resolution of Severe Malnutrition in Children With Sickle Cell Anemia in a Low‐Income Setting: A Prospective Single‐Arm Extension Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with sickle cell anemia (SCA) in low‐income settings are at risk of severe malnutrition, but optimal nutritional management has not been established. We evaluated an intensified ready‐to‐use therapeutic food (RUTF) regimen in children with persistent severe malnutrition after initial treatment and assessed whether early ...
Safiya Gambo, Shehu Umar Abdullahi, Hassan Adam Murtala, Halima Kabir, Khadija A. Shamsu, Sari A. Acra, Virginia A. Stallings, Mark Rodeghier, Michael R. DeBaun, Lauren J. Klein   +9 more
wiley   +1 more source

Machine learning algorithms for predicting unemployment duration in Russia [PDF]

Russian Journal of Economics
Predictions of the individual unemployment duration will allow to distribute target support while searching for a job more effectively. The paper uses survival models to predict the unemployment duration based on data from Russian employment centers in ...
Anna A. Maigur
doaj   +3 more sources

Triglyceride to high-density lipoprotein cholesterol ratio is associated with regression to normoglycemia from prediabetes in adults: a 5-year cohort study in China

Journal of Translational Medicine, 2023
Objective The current body of evidence on the association between the ratio of triglycerides to high-density lipoprotein cholesterol (TG/HDL-c) and the reversal of prediabetes to normoglycemia remains limited.
Zhiqiang Huang, Yong Han, Haofei Hu, Changchun Cao, Dehong Liu, Zhibin Wang   +5 more
doaj   +1 more source

Central Nervous System Tumors Among Infants in Canada: A Report From CYP‐C

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) tumors in infants are rare, pose unique clinical challenges, and lack large‐scale evidence‐based data to guide management. This study seeks to describe CNS tumors in Canadian infants and to compare their outcomes with those of older children.
Samuel Sassine, Hallie Coltin, Sylvia Cheng, Lucie Lafay‐Cousin, Vanan Issai Magimairajan, Craig Erker, Stéphanie Vairy, Lynette Bowes, Adam Fleming, Donna Johnston, Sarah McKillop, Roona Sinha, Julie Bennett, Christina Coleman, Laura Wheaton, Shayna Zelcer, Samuele Renzi, Thai Hoa Tran   +17 more
wiley   +1 more source

A simulation study comparing the power of nine tests of the treatment effect in randomized controlled trials with a time-to-event outcome

Trials, 2020
Background The logrank test is routinely applied to design and analyse randomized controlled trials (RCTs) with time-to-event outcomes. Sample size and power calculations assume the treatment effect follows proportional hazards (PH). If the PH assumption
Patrick Royston, Mahesh K. B. Parmar
doaj   +1 more source

Impact of Radiation Therapy on Physical and Psychosocial Health of Adolescents and Young Adults: A Joint Report From the Children's Oncology Group AYA and Radiation Oncology Committees

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Rates of cancer among adolescents and young adults (AYA), age 15–39 years, are increasing. Consequently, radiation oncologists are treating more AYAs who have diagnoses spanning both pediatric and adult practices. Compared to pediatric and older adult patients, AYAs face a unique set of challenges.
Hesham Elhalawani, Rachel K. Peterson, Avani D. Rao, Laurie J. McKenzie, Ahmed Magdy Elmotayam, Leslie Chang, Michael Roth, Susan L. McGovern   +7 more
wiley   +1 more source

Estimation of combined treatment effects by restricted mean survival time

Trials
Background Restricted mean survival time (RMST) endpoints are becoming commonly used as trialists look to analyse time-to-event outcomes without the restrictions of the proportional hazards assumption. An additional benefit of RMST endpoints which has so
Emily Alger, David S. Robertson, Abigail J. Burdon   +2 more
doaj   +1 more source

The Association between the Use of Proton Pump Inhibitors and the Risk of Hypomagnesemia in a National Cohort of Veteran Patients with HIV

Journal of the International Association of Providers of AIDS Care, 2019
Objectives: To examine the risk of hypomagnesemia of HIV-positive patients adherent to proton pump inhibitors (PPIs). Methods: A cohort study utilizing the Veterans Affairs Informatics and Computing Infrastructure was conducted on patients with (1) a ...
S. Scott Sutton PharmD, Joseph Magagnoli MS, Tammy Cummings PhD, James W. Hardin PhD   +3 more
doaj   +1 more source