Results 71 to 80 of about 10,758,008 (293)

SAS macros for point and interval estimation of area under the receiver operating characteristic curve for non-proportional and proportional hazards Weibull models

, 2010
Aims and objectives For prediction of risk of cardiovascular end points using survival models the proportional hazards assumption is often not met. Thus, non-proportional hazards models are more appropriate for developing risk prediction equations in ...
Stevenson, Christopher E., Mannan, Haider R. (R18333)   +1 more
core   +3 more sources

The non-linear link between non-high-density lipoprotein to high-density lipoprotein ratio and the risk of stroke in middle-aged and older adults in Chinese: a prospective cohort study from the China health and retirement longitudinal study

Frontiers in Endocrinology
ObjectiveThis study aims to assess the association between the non-HDL-c/HDL-c ratio and stroke risk among middle-aged and older adults participating in the China Health and Retirement Longitudinal Study (CHARLS).MethodsThis study conducted a prospective
Lanbo Wang, Yong Han, Yong Han, Changchun Cao, Haofei Hu, Haofei Hu, Han Li   +6 more
doaj   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

Current topics on treatment comparison for survival endpoints with non-proportional hazards

, 2021
The proportional hazards (PH) assumption is the key assumption which may need to be examined in each survival analysis. It is the underlying assumption for the Cox proportional hazards and the log-rank test achieves its maximum efficiency when the PH ...

core   +1 more source

A comparative analysis on characteristics and mortalities of four key transmission populations on antiretroviral therapy: a retrospective cohort study in Northwest China

BMC Infectious Diseases, 2022
Background This study explored disparities in characteristics and mortalities among four major transmission groups on antiretroviral therapy in northwest China as well as the survival impact of each transmission route.
Shuo Feng, Zirong Zhu, Pengju Yang, Juan Jin, Huihui Tuo, Ning Wang, Ruimin Bai, Yan Sun, Liumei Song, Xiu Zhang, Shengbang Wang, Qiqi Duan, Yingjian Huang, Yan Zheng, Songhua Xu   +14 more
doaj   +1 more source

Estimation of treatment effect under non‐proportional hazards and conditionally independent censoring [PDF]

Statistics in Medicine, 2012
In clinical trials with time‐to‐event outcomes, it is common to estimate the marginal hazard ratio from the proportional hazards model, even when the proportional hazards assumption is not valid. This is unavoidable from the perspective that the estimator must be specified a priori if probability statements about treatment effect estimates are desired.
Adam P, Boyd, John M, Kittelson, Daniel L, Gillen   +2 more
openaire   +2 more sources

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source

Increased Risk of Pulmonary Tuberculosis in Patients with Depression: A Cohort Study in Taiwan

Frontiers in Psychiatry, 2017
Background/objectiveTuberculosis (TB) and depression were major public health issues worldwide and the mutual causative relationships between them were not exhaustive. This study was performed to explore the association between depression, comorbidities,
Kao-Chi Cheng, Kao-Chi Cheng, Kuan-Fu Liao, Kuan-Fu Liao, Kuan-Fu Liao, Cheng-Li Lin, Cheng-Li Lin, Shih-Wei Lai, Shih-Wei Lai   +8 more
doaj   +1 more source

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin, Berrak Itır Aylı, Nüket Paksoy   +2 more
wiley   +1 more source

Analyzing Non-proportional Hazards: Use of the MRH Package

, 2016
In this manuscript we demonstrate the analysis of right-censored survival outcomes using the MRH package in R. The MRH package implements the multi-resolution hazard (MRH) model, which is a Polya-tree based, Bayesian semi-parametric method for flexible estimation of the hazard rate and covariate effects. The package allows for covariates to be included
Hagar, Yolanda, Dukic, Vanja
openaire   +2 more sources