Results 41 to 50 of about 79,182 (234)

Low-Cycle Fatigue of Aa2124t851 [PDF]

Transactions of the VŠB-Technical University of Ostrava, Mechanical Series, 2016
This paper presents an overview of extensive set fatigue tests results in low-cycle domain carried out at the Department of Applied Mechanics at the VŠB – Technical University of Ostrava on smooth specimens made of 2124T851 aluminum alloy.
Radim Halama, Martin Fusek, Ludmila Adámková, František Fojtík   +3 more
doaj   +1 more source

Experiments on Damage and Failure Behavior of Biaxially Loaded Specimens under Non-Proportional Load Paths

Physical Sciences Forum, 2022
This paper discusses new experiments with the X0-specimen taken from steel sheets and numerical simulations to investigate the influence of proportional and non-proportional loading on damage and failure processes in the moderate stress state regime. The
Moritz Zistl, Steffen Gerke, Michael Brünig   +2 more
doaj   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Effect of phase angle on the cyclic behavior of AISI 410 alloy [PDF]

MATEC Web of Conferences, 2019
Multiaxial strain-controlled fatigue tests were conducted on AISI 410 according to ASTM 2207-E08 [1] under proportional (phase angle, θ = 90°) and non-proportional (phase angle, θ = 90º) loadings.
Adinoyi Muhammed J., Merah Nesar, Albinmousa Jafar   +2 more
doaj   +1 more source

A survey on multiaxial fatigue damage parameters under non‐proportional loadings [PDF]

Fatigue & Fracture of Engineering Materials & Structures, 2017
AbstractIn this paper, several multiaxial fatigue damage parameters taking into account nonproportional additional hardening are reviewed. According to the way nonproportional additional hardening is considered in the model, the damage parameters are classified into 2 categories: (1) equivalent damage parameters and (2) direct damage parameters.
Luo, P., Yao, W., Susmel, L., Wang, Y., Ma, X.   +4 more
openaire   +2 more sources

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Study of Experimental Hysteresis Loops Under Non-Proportional Loading

Engineer: Journal of the Institution of Engineers, Sri Lanka, 2021
Fatigue life prediction is a challenge for engineers when it comes under nonproportionalloading. In many applications, engineering components are subjected to complicated states of stress and strain. Studying of hysteresis behavior under non proportional loading is important for reliable engineering designing for studying the cyclic deformation that is
openaire   +2 more sources

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Evaluation of multiaxial low cycle fatigue life under non-proportional loading considering effect of mean strain (Loading simulated thermal fatigue due to temperature fluctuation in junction piping)

Nihon Kikai Gakkai ronbunshu, 2020
In a pressure vessel, a heat exchanger and a junction piping where cold and hot water are mixed, temperature fluctuation yields multiaxial stress and random amplitude loading conditions.
Takahiro MORISHITA, Takamoto ITOH, Naoto KASAHARA   +2 more
doaj   +1 more source