Results 71 to 80 of about 299,681 (266)

Physical activity to improve cognition in older adults: can physical activity programs enriched with cognitive challenges enhance the effects? A systematic review and meta-analysis [PDF]

open access: yes, 2018
: EPHPP quality rating scores (DOCX 38 ...
A Damirchi   +82 more
core   +7 more sources

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

open access: yesFEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom   +3 more
wiley   +1 more source

Effects of Drug Administration on Postoperative Pain in Orthognathic Surgery: A Systematic Review

open access: yesClinical and Experimental Dental Research
Objectives This systematic review aims to offer indications on how drug administration affects postoperative pain in patients undergoing orthognathic surgery.
Gianna Dipalma   +11 more
doaj   +1 more source

Minimally invasive versus open pancreatoduodenectomy for pancreatic and peri-ampullary neoplasm (DIPLOMA-2): study protocol for an international multicenter patient-blinded randomized controlled trial

open access: yesTrials, 2023
Background Minimally invasive pancreatoduodenectomy (MIPD) aims to reduce the negative impact of surgery as compared to open pancreatoduodenectomy (OPD) and is increasingly becoming part of clinical practice for selected patients worldwide.
Nine de Graaf   +28 more
doaj   +1 more source

Selective serotonin reuptake inhibitors (SSRIs) for stroke recovery. [PDF]

open access: yes, 2011
BACKGROUND: Stroke is the major cause of adult disability. Selective serotonin reuptake inhibitors (SSRIs) have been used for many years to manage depression.
Anne Claxton   +6 more
core   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

Metodología de los tipos y diseños de estudio más frecuentemente utilizados en investigación clínica

open access: yesRevista Médica Clínica Las Condes, 2019
RESUMEN: Los estudios observacionales (EO) corresponden a diseños de investigación cuyo objetivo es “la observación y registro” de acontecimientos sin intervenir en el curso natural de estos.
Carlos Manterola   +3 more
doaj   +1 more source

Whole Body Vibration Treatments in Postmenopausal Women Can Improve Bone Mineral Density: Results of a Stimulus Focussed Meta-Analysis. [PDF]

open access: yesPLoS ONE, 2016
Whole body vibration treatment is a non-pharmacological intervention intended to stimulate muscular response and increase bone mineral density, particularly for postmenopausal women.
Antonio Fratini   +2 more
doaj   +1 more source

Does soy protein supplementation affect body composition in healthy exerciser adults? A systematic review and meta-analysis of clinical trials [PDF]

open access: yes, 2019
Background objectives: The effects of soy protein supplementation on anthropometric parameters and body composition indices of healthy adults is equivocal.
Asbaghi, O.   +6 more
core   +3 more sources

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