Results 171 to 180 of about 21,275,692 (207)
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Gefitinib in non-small cell lung cancer
Expert Opinion on Pharmacotherapy, 2005Gefitinib (Iressa), an orally-active tyrosine kinase inhibitor of the epidermal growth factor receptor (EGFR), is the first approved molecular-targeted drug for the management of patients with advanced non-small cell lung cancer (NSCLC). Two Phase II trials (IDEAL [Iressa Dose Evaluation in Advanced Lung Cancer]-1 and -2), evaluated the efficacy of ...
Kenji, Tamura, Masahiro, Fukuoka
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Paclitaxel for non-small cell lung cancer
Expert Opinion on Pharmacotherapy, 2004Paclitaxel, a tubulin-binding agent, is widely used for the treatment of non-small cell lung cancer (NSCLC). The combination of paclitaxel and a platinum compound is an approved regimen for the treatment of advanced NSCLC. The dose-limiting toxicity of paclitaxel is myelosuppression when administered on a prolonged infusion schedule, whereas neuropathy
Sakkaraiappan, Ramalingam +1 more
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Surgery for non-small cell lung cancer
Lung Cancer, 2001Although never proven to be superior in a randomized trial, surgical resection remains the treatment of choice for early stage non-small cell lung cancer (NSCLC). In stages IA, IB, IIA, IIB and selected stages IIIA surgical treatment offers the best long-term prognosis when a complete resection can be performed.
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Imaging of Non–Small Cell Lung Cancer
Radiologic Clinics of North America, 2005Radiologic evaluation is an important component of the clinical staging evaluation of lung cancer and can greatly influence whether the patient is treated with surgical resection, radiation therapy, chemotherapy, or a combination of these modalities. In addition to staging, the radiologic evaluation of the patient undergoing treatment and subsequent ...
Reginald F, Munden, John, Bruzzi
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Radiotherapy for non-small cell lung cancer
Lung Cancer, 2001This article shortly reviews the role of external-beam radiotherapy in the management of NSCLC with the focus on novel therapeutic approaches. The following applications of radiotherapy are addressed: definitive treatment in localized inoperable disease, radiotherapy as an adjunct to surgery (preoperative and postoperative), and palliative chest ...
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Allelotype of non-small cell lung cancer
International Journal of Oncology, 1996Loss of heterozygosity (LOH) studies have been used extensively to identify regions on chromosomes that may contain putative tumour suppressor genes. We have undertaken extensive allelotyping of 45 specimens of non-small cell lung cancer (NSCLC) using 92 polymorphic microsatellite markers on 39 chromosome arms. The most frequent allelic imbalances were
E, Neville +7 more
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Ifosfamide in Non-Small Cell Lung Cancer
Oncology, 2003In recent years the role of chemotherapy in advanced non-small cell lung cancer (NSCLC) has been well established. Ifosfamide is an old drug still considered an effective cytostatic agent in the treatment of NSCLC. As a single agent, it has showed a response rate of 20–25%.
C, Boni, F, Zanelli
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Chemotherapy and non-small-cell lung cancer
Drug and Therapeutics Bulletin, 2002Around 34,000 people in the UK die from lung cancer each year.1 Over 75% of patients with the disease have non-small-cell lung cancer (NSCLC). Here, we discuss the role of chemotherapy in the management of NSCLC, a treatment that some medical oncologists estimate would benefit 50% of patients with NSCLC,2 but which is given to fewer than 10 ...
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Immunotherapy for non-small cell lung cancer
JAAPA, 2019ABSTRACT Immunotherapy is a new genre of treatment for patients with advanced cancer. Initially approved for use in metastatic melanoma, immunotherapy has found a significant place in treating non-small cell lung cancer (NSCLC). Clinical trials using several combinations of immunotherapy are underway to help to determine the best treatment ...
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