Results 81 to 90 of about 1,335,871 (234)

DNA Methylation and Non-small Cell Lung Cancer [PDF]

, 2010
Genomic DNA methylation is a major form of epigenetic modification. Hypermethylation could affect the binding of transcription factors to DNA and change the structure of chromatin resulting in silence of tumor suppressor genes, which plays an important ...
Longbang CHEN, Youwei ZHANG
core  

Impact of adjuvant immunotherapy on prognosis in esophageal squamous cell carcinoma patients following neoadjuvant immunochemotherapy

Frontiers in Oncology
IntroductionThe CheckMate-577 trial confirmed that adjuvant nivolumab significantly prolonged disease-free survival (DFS) in patients with esophageal cancer who had residual disease after neoadjuvant chemoradiotherapy (nCRT).
Jiayi Geng, Jiayi Geng, Jiayi Geng, Jiayi Geng, Jiayi Geng, Bengang Hui, Teng Mu, Ni Ping , Runmin Jiang, Xiuyuan Chen, Xiuyuan Chen, Xiuyuan Chen, Xiuyuan Chen, Xiuyuan Chen, Heng Zhao, Heng Zhao, Heng Zhao, Heng Zhao, Heng Zhao, Dan zeng duo ji , Xizhao Sui, Xizhao Sui, Xizhao Sui, Xizhao Sui, Xizhao Sui, Yun Li, Yun Li, Yun Li, Yun Li, Yun Li, Xun Wang, Xun Wang, Xun Wang, Xun Wang, Xun Wang, Jie Lei   +35 more
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Systemic treatment of non-small cell lung cancer brain metastases

Contemporary Oncology, 2016
In the systemic treatment of brain metastases from non-small cell lung cancer (BMF-NSCLC) chemo- and targeted therapy are used. Response rates after platinum-based chemotherapy, range from 23% to 45%.
Ida Cedrych, Maksymilian A. Kruczała, Tomasz Walasek, Jerzy Jakubowicz, Paweł Blecharz, Marian Reinfuss   +5 more
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LncRNA MIR503HG Inhibits Non-Small Cell Lung Cancer Cell Proliferation by Inducing Cell Cycle Arrest Through the Downregulation of Cyclin D1

Cancer Management and Research, 2020
Shufen Xu,* Shengping Zhai,* Tiantian Du,* Zhan Li Respiratory Department, Yantai Yuhuangding Hospital Affiliated to Qingdao University, Yantai City, Shandong Province 264000, People’s Republic of China*These authors contributed equally to this ...
Xu S, Zhai S, Du T, Li Z
doaj  

Consensus on Application of Third-generation EGFR-TKI in EGFR Mutated NSCLC 
(2022 Version)

Chinese Journal of Lung Cancer, 2022
Chinese Society of Clinical Oncology (CSCO) Non-small Cell Lung Cancer Committee, Anti-cancer Drug Safety Management Committee (ASMC)   +1 more
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The Impact of Smoking Status on the Efficacy of Erlotinib in Patients with Advanced Non-small Cell Lung Cancer [PDF]

, 2009
Background and objective Erlotinib is a targeted treatment for advanced non-small cell lung cancer. Smoking status may be one of influencing factors of the efficacy of erlotinib.
Jinji YANG, Riqiang LIAO, Yan YANG, Yilong WU, Yisheng HUANG, Yujuan HUANG   +5 more
core  

Clinicopathological and molecular features of non-small cell lung cancer that transform to small-cell lung cancer: Case reports and literature review

Polish Journal of Pathology
The purpose of this study is to explore the clinical and pathological characteristics as well as the molecular pathogenesis of patients with non-small cell lung cancer (NSCLC) transforming into small cell lung cancer (SCLC). We investigated 14 patients
Qiqi Gao, Lixin Zhang, Yulong Zheng
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Mortalin overexpression predicts poor prognosis in early stage of non–small cell lung cancer

Tumor Biology, 2017
Mortalin is a member of the heat shock protein 70 family, which is involved in multiple cellular processes and may play key roles in promoting carcinogenesis.
Jie Sun, Shuan-Long Che, Jun-Jie Piao, Ming Xu, Li-Yan Chen, Zhen-Hua Lin   +5 more
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Non-small cell lung cancer: the era of targeted therapy

Lung Cancer: Targets and Therapy, 2012
Mara B Antonoff, Jonathan D'CunhaDivision of Thoracic and Foregut Surgery, Department of Surgery, University of Minnesota, Minneapolis, MN, USAAbstract: In this review, the authors aim to provide an overview of current molecular targeted ...
Antonoff MB, D'Cunha J
doaj  

Development and validation of an integrated system for lung cancer screening and post-screening pulmonary nodules management: a proof-of-concept study (ASCEND-LUNG)Research in context

EClinicalMedicine
Summary: Background: In order to address the low compliance and dissatisfied specificity of low-dose computed tomography (LDCT), efficient and non-invasive approaches are needed to complement its limitations for lung cancer screening and management. The
Yichen Jin, Wei Mu, Yezhen Shi, Qingyi Qi, Wenxiang Wang, Yue He, Xiaoran Sun, Bo Yang, Peng Cui, Chengcheng Li, Fang Liu, Yuxia Liu, Guoqiang Wang, Jing Zhao, Yuzi Zhang, Shuaitong Zhang, Caifang Cao, Chao Sun, Nan Hong, Shangli Cai, Jie Tian, Fan Yang, Kezhong Chen   +22 more
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