Results 11 to 20 of about 28,670,648 (221)

Effects of Taiwanofungus camphoratus on non-specific and specific immune activities in mice

Mycology, 2018
Taiwanofungus camphoratus is a precious medicinal fungus endemic to Taiwan and has been used as traditional medicine for a long time. Many pharmacological studies have revealed that T.
Yun-Yu Chen, Chiu-Ping Lo, Chin-Chung Lin, Yi-Hsuan Hsieh   +3 more
doaj   +2 more sources

Implications of Non-Specific Effects for Testing, Approving, and Regulating Vaccines. [PDF]

Drug Saf, 2023
The current framework for testing and regulating vaccines was established before the realization that vaccines, in addition to their effect against the vaccine-specific disease, may also have “non-specific effects” affecting the risk of unrelated ...
Benn CS, Amenyogbe N, Björkman A, Domínguez-Andrés J, Fish EN, Flanagan KL, Klein SL, Kollmann TR, Kyvik KO, Netea MG, Rod NH, Schaltz-Buchholzer F, Shann F, Selin L, Thysen SM, Aaby P.   +15 more
europepmc   +2 more sources

Beneficial non-specific effects of live vaccines against COVID-19 and other unrelated infections. [PDF]

Lancet Infect Dis, 2023
Live attenuated vaccines could have beneficial, non-specific effects of protecting against vaccine-unrelated infections, such as BCG protecting against respiratory infection.
Aaby P, Netea MG, Benn CS.
europepmc   +2 more sources

Evidence-Based Approach to One Health Vaccinology [PDF]

Archives of Razi Institute, 2021
Only a few human vaccine trials have been reported from the least developed countries. The target population of biological products often does not have the same opportunity to participate in pre-and post-licensing studies (1). The COVID-19 vaccine trials
Z Baradaran Seyed
doaj   +1 more source

One vaccine to counter many diseases? Modeling the economics of oral polio vaccine against child mortality and COVID-19

Frontiers in Public Health, 2022
IntroductionRecent reviews summarize evidence that some vaccines have heterologous or non-specific effects (NSE), potentially offering protection against multiple pathogens.
Angela Y. Chang, Angela Y. Chang, Peter Aaby, Peter Aaby, Michael S. Avidan, Christine S. Benn, Christine S. Benn, Christine S. Benn, Stefano M. Bertozzi, Stefano M. Bertozzi, Stefano M. Bertozzi, Lawrence Blatt, Lawrence Blatt, Konstantin Chumakov, Konstantin Chumakov, Shabaana A. Khader, Shyam Kottilil, Shyam Kottilil, Madhav Nekkar, Mihai G. Netea, Mihai G. Netea, Mihai G. Netea, Annie Sparrow, Dean T. Jamison   +23 more
doaj   +1 more source

The impact of specific and non-specific immunity on the ecology of Streptococcus pneumoniae and the implications for vaccination [PDF]

, 2013
More than 90 capsular serotypes of Streptococcus pneumoniae coexist despite competing for nasopharyngeal carriage and a gradient in fitness. The underlying mechanisms for this are poorly understood and make assessment of the likely population impact of ...
Robertson, Charles, Edmunds, W. John, Flasche, Stefan, Goldblatt, David, Yoon Hong, Choi, Miller, Elizabeth   +5 more
core   +5 more sources

Does Influenza Vaccination during Pregnancy Have Effects on Non-Influenza Infectious Morbidity? A Systematic Review and Meta-Analysis of Randomised Controlled Trials

Vaccines, 2021
The recommendation to provide inactivated influenza vaccine (IIV) to pregnant women is based on observed protection against influenza-related morbidity in mother and infant.
Katrine Pedersbæk Hansen, Christine Stabell Benn, Thomas Aamand, Martin Buus, Isaquel da Silva, Peter Aaby, Ane Bærent Fisker, Sanne Marie Thysen   +7 more
doaj   +1 more source

MicroRNA mimics can distort physiological microRNA effects on immune checkpoints by triggering an antiviral interferon response

RNA Biology, 2022
The microRNA-200 family has wide-ranging regulatory functions in cancer development and progression. Above all, it is strongly associated with the epithelial-to-mesenchymal transition (EMT), a process during which cells change their epithelial to a ...
Felix Prinz, Katharina Jonas, Amar Balihodzic, Christiane Klec, Andreas Reicher, Dominik Andreas Barth, Jakob Riedl, Armin Gerger, Tobias Kiesslich, Christian Mayr, Beate Rinner, Julia Kargl, Martin Pichler   +12 more
doaj   +1 more source

Self reported aggravating activities do not demonstrate a consistent directional pattern in chronic non specific low back pain patients: An observational study [PDF]

, 2009
Question: Do the self-reported aggravating activities of chronic non-specific low back pain patients demonstrate a consistent directional pattern? Design: Cross-sectional observational study.
Wand, Benedict M, Marston, L, McAuley, James, McAuley, J, Rebecca Hunter, Louise Marston, O'Connell, NE, Wand, BM, Hunter, R, Hunter, Rebecca, Neil E. O’Connell, Marston, Louise, Benedict M. Wand, James McAuley, O\u27Connell, Neil E   +14 more
core   +5 more sources

Oral polio revaccination is associated with changes in gut and upper respiratory microbiomes of infants

Frontiers in Microbiology, 2022
After the eradication of polio infection, the plan is to phase-out the live-attenuated oral polio vaccine (OPV). Considering the protective non-specific effects (NSE) of OPV on unrelated pathogens, the withdrawal may impact child health negatively ...
Márcia Melo Medeiros, Anna Cäcilia Ingham, Line Møller Nanque, Line Møller Nanque, Claudino Correia, Marc Stegger, Paal Skyt Andersen, Ane Baerent Fisker, Ane Baerent Fisker, Christine Stabell Benn, Christine Stabell Benn, Christine Stabell Benn, Miguel Lanaspa, Henrique Silveira, Patrícia Abrantes   +14 more
doaj   +1 more source