Results 61 to 70 of about 385 (111)
Construction of Recombinant Baculoviruses Expressing Infectious Bursal Disease Virus Main Protective Antigen and Their Immune Effects on Chickens. [PDF]
PLoS ONE, 2015 In order to overcome the limitations of conventional vaccines for infectious bursal disease virus (IBDV), we constructed recombinant dual expression system baculoviruses with VP2 and VP2/4/3, the main protective antigens of IBDV.
Jingping Ge +4 more
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Expert Review of Vaccines, 2017 Introduction: Vaccines have heterologous effects on the immune system, leading to altered susceptibility to a range of pathogens, and possibly allergy and autoimmunity. Effects are often sex-differential.
Katie L. Flanagan, Magdalena Plebanski
doaj +1 more source
Non-specific effects of vaccines: RCTs, not observational studies, are needed: Figure 1
Archives of Disease in Childhood, 2012 For more than 15 years, Peter Aaby and colleagues have been studying mortality after infant vaccination in various sub-Saharan African populations and describing ‘non-specific’ or ‘heterologous’ effects of the vaccines on infant death.1,–,11 In summary, Aaby's observations suggest that live vaccines such as BCG and measles reduce all-cause mortality ...
openaire +4 more sources
On the investigation of non-specific effects of BCG: Interpreting global vaccine data [PDF]
eBioMedicine, 2021 Ane Bærent Fisker +1 more
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Determinants of BCG scarification among children in rural Guinea-Bissau: A prospective cohort study
Human Vaccines & Immunotherapeutics, 2018 Background: Bacillus Calmette-Guérin (BCG) vaccination may have beneficial non-specific effects on child survival, the effects being stronger for children developing a scar. In a prospective cohort study, we examined determinants for not developing a BCG
Katarina M. Funch +6 more
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Neonatal Immunization: Rationale, Current State, and Future Prospects
Frontiers in Immunology, 2018 Infections take their greatest toll in early life necessitating robust approaches to protect the very young. Here, we review the rationale, current state, and future research directions for one such approach: neonatal immunization. Challenges to neonatal
Elizabeth Whittaker +4 more
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Expert Review of Vaccines, 2018 Introduction: Emerging evidence suggests that vaccines, in addition to their disease-specific effects, have important non-specific effects (NSEs), which contribute to their overall effect on mortality and morbidity.
Christine Stabell Benn +4 more
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Tropical Medicine & International Health, 2009 SummaryRoutine vaccination programmes have led to substantial declines in the incidence of most of the target diseases. In these circumstances, vaccine effects beyond those on the target diseases may become evident. Several studies have suggested that certain vaccines may influence mortality in low income settings in ways that cannot be attributed to ...
Paul E. M. Fine +9 more
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Choice and Design of Adjuvants for Parenteral and Mucosal Vaccines
Vaccines, 2015 The existence of pathogens that escape recognition by specific vaccines, the need to improve existing vaccines and the increased availability of therapeutic (non-infectious disease) vaccines necessitate the rational development of novel vaccine concepts ...
Huub F. J. Savelkoul +3 more
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VaccinesThe emergence of COVID-19 caused by SARS-CoV-2 prompted an unprecedented global response to develop vaccines at an accelerated pace. Messenger RNA (mRNA) and adenovirus vector vaccines emerged as the frontrunners in global immunization efforts ...
Laura Alves Ribeiro Oliveira +5 more
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