Results 61 to 70 of about 1,099,174 (311)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Non-state actors and the use of force [PDF]

open access: yes, 2015
No description ...
Henderson, Christian
core  

Interacting State and Non-State Actors in Hybrid Settings of Public Service Delivery [PDF]

open access: yes, 2015
Public services are increasingly delivered through hybrid settings of state and non-state actors. A key characteristic of such settings is the interaction between these actors.
Van der Heijden, Jeroen
core   +3 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Activities of Non-State Actors and Redefining the Concept of International Legal Personality [PDF]

open access: yesپژوهشهای حقوقی
A controversial issue in international law is how international legal personality is defined or by what criteria it is conferred. The field mainly tries to address the questions that who has international legal personality, and what characteristics the ...
Pouria Askari, Zahra MoshrefJavadi
doaj   +1 more source

Fetal Brain Tumor Harboring a Unique ROCK1::BRAF Fusion

open access: yes
Pediatric Blood &Cancer, EarlyView.
Marllon Cindra Sant'Ana   +8 more
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

The Guiding Principles and armed non-State actors

open access: yesForced Migration Review, 2018
Millions of internally displaced persons live in areas controlled by armed non-State actors. Direct humanitarian engagement with these actors is required in order to help them improve their understanding of and compliance with the Guiding Principles on ...
Carla Ruta   +2 more
doaj  

Non-state actors and cultural heritage: Friends or foes? [PDF]

open access: yes, 2015
Los actores no estatales más activos y reivindicativos en el ámbito del patrimonio cultural son las organizaciones no gubernamentales (ONG), las empresas privadas, y los grupos armados no estatales.
Chechi, Alessandro
core   +1 more source

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