Results 61 to 70 of about 1,099,174 (311)
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Interacting State and Non-State Actors in Hybrid Settings of Public Service Delivery [PDF]
Public services are increasingly delivered through hybrid settings of state and non-state actors. A key characteristic of such settings is the interaction between these actors.
Van der Heijden, Jeroen
core +3 more sources
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Activities of Non-State Actors and Redefining the Concept of International Legal Personality [PDF]
A controversial issue in international law is how international legal personality is defined or by what criteria it is conferred. The field mainly tries to address the questions that who has international legal personality, and what characteristics the ...
Pouria Askari, Zahra MoshrefJavadi
doaj +1 more source
Fetal Brain Tumor Harboring a Unique ROCK1::BRAF Fusion
Pediatric Blood &Cancer, EarlyView.
Marllon Cindra Sant'Ana +8 more
wiley +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
The Guiding Principles and armed non-State actors
Millions of internally displaced persons live in areas controlled by armed non-State actors. Direct humanitarian engagement with these actors is required in order to help them improve their understanding of and compliance with the Guiding Principles on ...
Carla Ruta +2 more
doaj
Non-state actors and cultural heritage: Friends or foes? [PDF]
Los actores no estatales más activos y reivindicativos en el ámbito del patrimonio cultural son las organizaciones no gubernamentales (ONG), las empresas privadas, y los grupos armados no estatales.
Chechi, Alessandro
core +1 more source

