Results 81 to 90 of about 209,064 (307)

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

UN environmental policy: Non-State Actors, trends, and the regulatory role of the state

open access: yesJournal of Political Ecology, 2017
This interdisciplinary article draws from the radical ideas of global political ecology (GPE), environmental politics, ecological economics and the sociological analysis of social movements.
Joseph S. Weiss   +6 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Violent non-state actors' patterns of power: The case of Hezbollah [PDF]

open access: yesJournal of Regional Security
Conventional International Relations emphasises the role of states as the primary actors, with control being the ultimate form of power. However, in today's interconnected and intricate global landscape, non-state actors, particularly violent non-state ...
Jaber Boushra
doaj   +1 more source

Transnational Elites in the ILO and the EESC: Do non-governmental actors matter? [PDF]

open access: yes, 2007
This paper is based on a comparative survey of the membership of the European Union’s Economic and Social Committee (EESC) and the International Labour Organisation’s Governing Body between 1990 and 2007.
Kissack, Robert.
core  

Non-state actors in international law /

open access: yes, 2020
"The role and position of non-state actors in international law is the subject of a long-standing and intensive scholarly debate. This book explores the participation of this new category of actors in an international legal system that has historically ...
Noortmann, Math.   +2 more
core   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Communication on Climate Change in the Mediterranean by Non-State Actors: A Framing Analysis

open access: yesAlternatif Politika
How do non-state actors frame climate change in a region labelled as a climate hotspot? To answer this question, this article explores the climate communication strategies of non-state actors with various country origins.
Iosif Botetzagıas, Emre İşeri
doaj   +1 more source

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