Results 71 to 80 of about 26,546,882 (300)

Why are Non-State Actors Able to Exercise Political Control?

open access: yes, 2020
Non-state actors and their ability to exercise political control have been at the forefront of American defense policy since the turn of the 21st century.
Julian, Hannan
core  

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Mapping the Participation of ASEAN Actors in International Climate Initiatives

open access: yesAsia & the Pacific Policy Studies
To make progress on decarbonisation, a large number and variety of stakeholders need to be engaged. In this Policy Forum, we assess the participation of different types of ASEAN actors in major international initiatives for climate action.
Ida Dokk Smith   +2 more
doaj   +1 more source

Non-State Military Actors: The Case of the 2011 Libyan Conflict [PDF]

open access: yesCentral European Journal of International & Security Studies, 2012
Non-state military actors (i.e. private military companies, contractors and/or militias) form an inherent part of the present global system. In many cases, however, the role and participation of non-state military actors appears to be rather ambiguous ...
Radana Makariusová, Zdeněk Ludvík
doaj  

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

The politics of surveillance and response to disease outbreaks: The new frontier for states and non-state actors

open access: yes, 2016
The capacity to conduct international disease outbreak surveillance and share information about outbreaks quickly has empowered both State and Non-State Actors to take an active role in stopping the spread of disease by generating new technical means to ...
Youde, JR, Davies, SE
core   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

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