Results 101 to 110 of about 122,879 (287)

Enhancing Tendon Regeneration: Investigating the Impact of Topography on the Secretome of Adipose‐Derived Stem Cells

Advanced Science, EarlyView.
The impact of topography on the secretome of adipose‐derived stem cells (ADSCs) has the potential for promoting tendon regeneration. The secretome generated from ADSCs on aligned structure has a potent effect in promoting cell migration, proliferation, tenogenic differentiation, macrophage M2 polarization, and tendon mechanical function recovery ...
Qiuzi Long, Chuanquan Liu, Haotian Zheng, Mingyue Wang, Hanmei Liu, Yue Liu, Zhicheng Cao, Yuzhi Sun, Qingyun Mo, Ludvig J. Backman, Jialin Zhu, Lizhi Hu, Jinlong Huang, Wei Zhang, Jialin Chen   +14 more
wiley   +1 more source

Does Helicobacter pylori Exacerbate Gastric Mucosal Injury in Users of Nonsteroidal Anti-Inflammatory Drugs? A Multicenter, Retrospective, Case-Control Study

Gut and Liver, 2016
Background/AimsThe interaction between nonsteroidal anti-inflammatory drugs (NSAIDs) and Helicobacter pylori remains controversial. We retrospectively investigated whether H.
doaj   +1 more source

H‐2 AND NON ‐H‐2 DETERMINED STRAIN VARIATION IN PALATAL SHELF AND TONGUE ADENOSINE 3’:5’CYCLIC MONOPHOSPHATE: A POSSIBLE ROLE IN THE ETIOLOGY OF STEROID‐INDUCED CLEFT PALATE [PDF]

, 1979
Robert P. Erickson, Martin S. Butley, Charles F. Sing   +2 more
openalex   +1 more source

FABP4 as a Mediator of Lipid Metabolism and Pregnant Uterine Dysfunction in Obesity

Advanced Science, EarlyView.
Obesity during late pregnancy contributes to uterine smooth muscle dysfunction, but the underlying mechanisms are unclear. This study identifies fatty acid binding protein 4 (FABP4) as a key player in the process, mediating excessive fatty acid uptake, lipid accumulation, and mitochondrial dysfunction in myometrial cells. FABP4 could be a novel uterine
Xuan Li, Huihui Yu, Ruixian Tian, Xingxing Wang, Ting Xing, Chenyi Xu, Tengteng Li, Xue Du, Qianqian Cui, Biao Yu, Yunxia Cao, Zongzhi Yin   +11 more
wiley   +1 more source

Characteristics of Hemorrhagic Peptic Ulcers in Patients Receiving Antithrombotic/Nonsteroidal Antiinflammatory Drug Therapy

Gut and Liver, 2012
Background/AimsAntithrombotic/nonsteroidal antiinflammatory drug (NSAID) therapies increase the incidence of upper gastrointestinal bleeding. The features of hemorrhagic peptic ulcer disease in patients receiving antithrombotic/NSAID therapies were ...
doaj   +1 more source

Cartilage‐Penetrating Framework Nucleic Acid Nanoparticles Ameliorate Osteoarthritis by Promoting Drug Delivery and Chondrocyte Uptake

Advanced Science, EarlyView.
Based on the poor cartilage penetration of tFNA, a novel tFNA‐2WL with excellent cartilage permeability and perfect chondrocyte endocytosis properties is designed and fabricated. As a result, tFNA‐2WL has a nearly seven‐fold increase in the penetration depth into the cartilage, with the same excellent cell entry properties as tFNA.
Kui Huang, Qiumei Li, Huixuan Lin, Qian Shen, Yaping Wu, Taoran Tian, Chuan Ma, Sirong Shi, Jingang Xiao, Yunfeng Lin   +9 more
wiley   +1 more source

Overprescribing of potentially harmful medication: an observational study in England’s general practice

BJGP Open
Background: Overprescribing of potentially harmful medication in UK general practice has a complex association with socioeconomic deprivation. Aim: To assess trends in general practice prescribing of five high-risk medications and their relationship with
Tasneem Khan, Bethan Copsey, Paul Carder, Stella Johnson, Mohammed Imran, Kaiwen Wang, Sarah Alderson   +6 more
doaj   +1 more source

Frontiers in Nondrug Treatment of Sarcopenia: A Review of Pathological Mechanisms and the Latest Treatment Strategies

AGING MEDICINE, EarlyView.
This article mainly introduces the pathologic process of sarcopenia and the recent progress in diagnosis and treatment, especially the nondrug treatment. ABSTRACT Sarcopenia refers to the progressive decline and wasting of skeletal muscle function, typically linked to aging or as a secondary effect of various conditions, including systemic inflammation,
Qi‐Fei Kuang, Yu‐Qing Ni, You‐Shuo Liu   +2 more
wiley   +1 more source

Appropriate Prescription of Non-Steroidal Anti-Inflammatory Drugs in Geriatric Patients—A Systematic Review

BioChem
The elderly population is growing worldwide. Non-steroidal anti-inflammatory drugs (NSAIDs) are commonly prescribed, but their adverse events can pose significant risks. Different NSAID molecules can exhibit varying risk profiles.
Carolina Costa, Diana Soares, Ana Borges, Ana Gonçalves, José Paulo Andrade, Hugo Ribeiro   +5 more
doaj   +1 more source

Preventive Efficacy and Safety of Rebamipide in Nonsteroidal Anti-Inflammatory Drug-Induced Mucosal Toxicity

Gut and Liver, 2014
Background/AimsThe use of proton pump inhibitors or misoprostol is known to prevent the gastrointestinal complications of nonsteroidal anti-inflammatory drugs (NSAIDs).
doaj   +1 more source