NORMAN guidance on suspect and non-target screening in environmental monitoring
Environmental Sciences Europe, 2023 Increasing production and use of chemicals and awareness of their impact on ecosystems and humans has led to large interest for broadening the knowledge on the chemical status of the environment and human health by suspect and non-target screening (NTS).
Juliane Hollender +33 more
doaj +1 more source
G protein-coupled receptors not currently in the spotlight: free fatty acid receptor 2 and GPR35 [PDF]
, 2017 It is widely appreciated that G protein-coupled receptors have been the most successfully exploited class of targets for the development of small molecule medicines. Despite this, to date, less than 15% of the non-olfactory G protein-coupled receptors in
Milligan, Graeme
core +1 more source
Searching for anthropogenic contaminants in human breast adipose tissues using gas chromatography-time-of-flight mass spectrometry [PDF]
, 2008 The potential of GC-TOF MS for screening anthropogenic organic contaminants in human breast adipose tissues has been investigated. Initially a target screening was performed for a list of 125 compounds which included persistent halogen pollutants (OC ...
Hernandez, Felix +3 more
core +1 more source
Molecular similarity for machine learning in drug development : poster presentation [PDF]
, 2008 Poster presentation In pharmaceutical research and drug development, machine learning methods play an important role in virtual screening and ADME/Tox prediction.
Proschak, Ewgenij +2 more
core +1 more source
Non-target screening of emerging contaminants in landfills: A review
Current Opinion in Environmental Science & Health, 2023 Leachate from landfills is considered an important point source of contamination, which poses significant threat to the receiving ecosystems and their resources. Therefore, it is necessary to monitor the occurrence of contaminants, and develop effective treatment processes, and to achieve this, target, suspect and non-target screening must be employed.
Nika, M.-C. +3 more
openaire +2 more sources
Development of a candidate reference material for adventitious virus detection in vaccine and biologicals manufacturing by deep sequencing. [PDF]
, 2016 Unbiased deep sequencing offers the potential for improved adventitious virus screening in vaccines and biotherapeutics. Successful implementation of such assays will require appropriate control materials to confirm assay performance and sensitivity.
Alin, Voskanian-Kordi +49 more
core +2 more sources
, 2018 We describe an efficient approximation for the electron-electron interaction in the determination of the low-energy effective interaction in multiband lattice systems.
Honerkamp, Carsten
core +1 more source
CAD in mammography: lesion-level versus case-level analysis of the effects of prompts on human decisions [PDF]
, 2008 Object: To understand decision processes in CAD-supported breast screening by analysing how prompts affect readers’ judgements of individual mammographic features (lesions).
Andrey A. Povyakalo +18 more
core +1 more source
Screening-Limited Response of NanoBiosensors [PDF]
, 2007 Despite tremendous potential of highly sensitive electronic detection of bio-molecules by nanoscale biosensors for genomics and proteomic applications, many aspects of experimentally observed sensor response (S) are unexplained within consistent ...
Alam, Muhammad A., Nair, Pradeep R.
core +1 more source
Charge state of C10 and C5 energetic cluster ions in amorphous carbon targets: simulations [PDF]
, 2006 We present here detailed simulations of the interaction of energetic C10 and C5 clusters at the energies of 1, 2, and 4 MeV per carbon atom with an amorphous carbon target.
Nardi, E., Tombrello, T. A.
core +1 more source