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Method validation strategies involved in non-targeted metabolomics

Journal of Chromatography A, 2014
Non-targeted metabolomics is the hypothesis generating, global unbiased analysis of all the small-molecule metabolites present within a biological system, under a given set of conditions. It includes several common steps such as selection of biological samples, sample pre-treatment, analytical conditions set-up, acquiring data, data analysis by ...
Shama, Naz   +3 more
openaire   +4 more sources

Integrating analytical resolutions in non-targeted wine metabolomics

Tetrahedron, 2015
Direct injection Fourier transform ion cyclotron resonance mass spectrometry (FTICR-MS), and ultra-high performance liquid chromatography coupled to mass spectrometry (UPLC/MS) were combined for the non-targeted analysis of wine metabolites. The unrivalled resolution on mass measurement allowed by the former and the separation ability of isomeric and ...
Roullier-Gall, C.   +5 more
openaire   +3 more sources

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