Results 41 to 50 of about 11,010,876 (174)

Metabolomics to unveil and understand phenotypic diversity between pathogen populations [PDF]

open access: yes, 2010
Leishmaniasis is a debilitating disease caused by the parasite Leishmania. There is extensive clinical polymorphism, including variable responsiveness to treatment.
t'Kindt, Ruben   +9 more
core   +2 more sources

Integrated Non-targeted and Targeted Metabolomics Uncovers Amino Acid Markers of Oral Squamous Cell Carcinoma

open access: yesFrontiers in Oncology, 2020
Purpose: It is very important to develop potential molecular associated with oral squamous cell carcinoma (OSCC) malignant transformation and progression.
Xi-Hu Yang   +11 more
doaj   +1 more source

Triple acquisition mass spectrometry (TRAM) combining targeted and non-targeted metabolomics in a single run [PDF]

open access: yes
We introduce TRAM, a triple acquisition strategy on high-speed, time-of-flight mass spectrometry for merging non-targeted and targeted metabolomics into one run.
Marvin, Glas   +10 more
core   +2 more sources

Non‐targeted metabolomics identify polyamine metabolite acisoga as novel biomarker for reduced left ventricular function

open access: yesESC Heart Failure, 2022
Aims Chronic heart failure with reduced ejection fraction remains a major health issue. To date, no reliable biomarker is available to predict reduced left ventricular ejection fraction (LV‐EF).
Andreas Puetz   +9 more
doaj   +1 more source

Non-targeted metabolomics reveals diagnostic biomarker in the plasma of patients with lung cancer. [PDF]

open access: yesOncol Lett
Lung cancers are malignant tumors with high incidence and mortality rates and a 5-year survival rate that depends on the stage at the time of diagnosis. Screening methods for lung cancer are becoming increasingly diverse, but existing approaches lack sensitivity or specificity for early lesions, posing notable challenges for the early diagnosis of lung
Liu Y   +9 more
europepmc   +3 more sources

Analysis of the Formation of Sauce-Flavored Daqu Using Non-targeted Metabolomics

open access: yesFrontiers in Microbiology, 2022
Sauce-flavored Daqu exhibits different colors after being stacked and fermented at high temperatures. Heiqu (black Daqu, BQ) with outstanding functions is difficult to obtain because its formation mechanism is unclear. In this study, we compared the metabolites in different types of Daqu using ultra-high-performance liquid chromatography triple ...
Shuai Luo   +10 more
openaire   +3 more sources

Non-Targeted Metabolomic Profiling Identifies Metabolites with Potential Antimicrobial Activity from an Anaerobic Bacterium Closely Related to Terrisporobacter Species

open access: yesMetabolites, 2023
This work focused on the metabolomic profiling of the conditioned medium (FS03CM) produced by an anaerobic bacterium closely related to Terrisporobacter spp. to identify potential antimicrobial metabolites.
Amila S. N. W. Pahalagedara   +6 more
doaj   +1 more source

Comparison of venous and fingertip plasma using non-targeted proteomics and metabolomics [PDF]

open access: yesTalanta, 2019
Blood tests, which are used to evaluate health status, are relatively non-invasive and provide a great deal of health-related information. Blood is usually collected using a standard venous blood sampling protocol, but it is possible to collect blood from a subject's fingertip, and previous studies have investigated whether fingertip-derived blood can ...
Nishiumi, Shin   +5 more
openaire   +3 more sources

Metabolomics and wood development [PDF]

open access: yes, 2013
The tree industry is one of Sweden's most important economic sectors, producing pulp, paper, wooden goods and wood as a bioenergy source. Understanding the biology behind the processes of tree growth and wood development is a key to maximizing the use of
Johansson, Annika I.
core   +1 more source

Untargeted-targeted metabolomics: energy metabolism characteristics in heart failure staging and discovery of novel biomarkers

open access: yesJournal of Translational Medicine
Background Heart Failure represents the severe stage of various heart diseases. Its global morbidity and mortality are on the rise, making it a serious public health issue that imposes a heavy burden on patients’ families and society.
Xiao Zhang   +4 more
doaj   +1 more source

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