Non-Targeted Metabolomics Analysis of Differences in Fruit Metabolites of Different Plum Varieties [PDF]
A total of 951 metabolites including 489 primary ones and 315 secondary ones were detected in plum fruit from 5 different varieties/lines in Guangdong by non-targeted metabolomics.
CHANG Xiaoxiao, PENG Cheng, CHEN Huiqiong, QIU Jishui, LU Yusheng
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Modern metabolomics platforms are able to identify many drug-related metabolites in blood samples. Applied to population-based biobank studies, the detection of drug metabolites can then be used as a proxy for medication use or serve as a validation tool
Karsten Suhre +6 more
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Metabolomic Approaches to Studying the Response to Drought Stress in Corn (Zea mays) Cobs
Metabolomics is a technique that allows for the evaluation of the entire extractable chemical profile of a plant, for example, using high-resolution mass spectrometry (HRMS) and can be used to evaluate plant stress responses, such as those due to drought.
Isabella Gaffney +4 more
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Capillary electrophoresis as a metabolomics tool for non-targeted fingerprinting of biological samples [PDF]
Metabolomics, understood as a data driven strategy trying to find markers of a situation under study without a priori hypothesis, has rapidly caught the attention and evolved from the simple pattern recognition strategy, which was a great innovation at its origins, to the interest for the final identification of markers responsible for class separation,
C, Barbas +2 more
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Leveraging open cheminformatics tools for non-targeted metabolomics analysis of C. elegans: a workflow comparison and application to strains related to xenobiotic metabolism and neurodegeneration [PDF]
Caenorhabditis elegans (C. elegans) is a well-established nematode model for studying metabolism and neurodegenerative disorders, such as Alzheimer’s (AD) and Parkinson’s disease (PD).
Lai, Yunjia +3 more
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Profile of cardiac lipid metabolism in STZ-induced diabetic mice
Background Lipotoxicity contributes to diabetic myocardial disease. In this study, we investigated the lipid species contributing to lipotoxicity and the relationship with peroxisomal β-oxidation in the heart of diabetic mice.
Wenjie Li +11 more
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Chemotherapy combined with checkpoint blockade antibodies targeting programmed cell death protein (PD‐1) has achieved remarkable success in non‐small cell lung cancer. However, few patients benefit from long‐term treatment.
Yaqing Liu +9 more
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A non-targeted metabolomics analysis identifies wound-induced oxylipins in Physcomitrium patens
Plant oxylipins are a class of lipid-derived signaling molecules being involved in the regulation of various biotic and abiotic stress responses. A major class of oxylipins are the circular derivatives to which 12-oxo-phytodienoic acid (OPDA) and its ...
Hanno Christoph Resemann +6 more
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The effect of root hairs on exudate composition: a comparative non-targeted metabolomics approach
AbstractRoot exudation is a major pathway of organic carbon input into soils. It affects soil physical properties, element solubility as well as speciation, and impacts the microbial community in the rhizosphere. Root exudates contain a large number of primary and secondary plant metabolites, and the amount and composition are highly variable depending
Martin Lohse +6 more
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Tomofuji et al. perform non-targeted metabolomics on serum samples from people with type 2 diabetes with or without complications. The authors identify metabolites associated with retinal and renal complications.
Yoshihiko Tomofuji +16 more
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