Results 51 to 60 of about 11,010,876 (174)

Non-Targeted Metabolomics Analysis of Differences in Fruit Metabolites of Different Plum Varieties [PDF]

open access: yesShipin Kexue
A total of 951 metabolites including 489 primary ones and 315 secondary ones were detected in plum fruit from 5 different varieties/lines in Guangdong by non-targeted metabolomics.
CHANG Xiaoxiao, PENG Cheng, CHEN Huiqiong, QIU Jishui, LU Yusheng
doaj   +1 more source

Matching Drug Metabolites from Non-Targeted Metabolomics to Self-Reported Medication in the Qatar Biobank Study

open access: yesMetabolites, 2022
Modern metabolomics platforms are able to identify many drug-related metabolites in blood samples. Applied to population-based biobank studies, the detection of drug metabolites can then be used as a proxy for medication use or serve as a validation tool
Karsten Suhre   +6 more
doaj   +1 more source

Metabolomic Approaches to Studying the Response to Drought Stress in Corn (Zea mays) Cobs

open access: yesMetabolites, 2021
Metabolomics is a technique that allows for the evaluation of the entire extractable chemical profile of a plant, for example, using high-resolution mass spectrometry (HRMS) and can be used to evaluate plant stress responses, such as those due to drought.
Isabella Gaffney   +4 more
doaj   +1 more source

Capillary electrophoresis as a metabolomics tool for non-targeted fingerprinting of biological samples [PDF]

open access: yesJournal of Pharmaceutical and Biomedical Analysis, 2011
Metabolomics, understood as a data driven strategy trying to find markers of a situation under study without a priori hypothesis, has rapidly caught the attention and evolved from the simple pattern recognition strategy, which was a great innovation at its origins, to the interest for the final identification of markers responsible for class separation,
C, Barbas   +2 more
openaire   +2 more sources

Leveraging open cheminformatics tools for non-targeted metabolomics analysis of C. elegans: a workflow comparison and application to strains related to xenobiotic metabolism and neurodegeneration [PDF]

open access: yes
Caenorhabditis elegans (C. elegans) is a well-established nematode model for studying metabolism and neurodegenerative disorders, such as Alzheimer’s (AD) and Parkinson’s disease (PD).
Lai, Yunjia   +3 more
core   +2 more sources

Profile of cardiac lipid metabolism in STZ-induced diabetic mice

open access: yesLipids in Health and Disease, 2018
Background Lipotoxicity contributes to diabetic myocardial disease. In this study, we investigated the lipid species contributing to lipotoxicity and the relationship with peroxisomal β-oxidation in the heart of diabetic mice.
Wenjie Li   +11 more
doaj   +1 more source

Changes in L‐phenylalanine concentration reflect and predict response to anti‐PD‐1 treatment combined with chemotherapy in patients with non‐small cell lung cancer

open access: yesMedComm
Chemotherapy combined with checkpoint blockade antibodies targeting programmed cell death protein (PD‐1) has achieved remarkable success in non‐small cell lung cancer. However, few patients benefit from long‐term treatment.
Yaqing Liu   +9 more
doaj   +1 more source

A non-targeted metabolomics analysis identifies wound-induced oxylipins in Physcomitrium patens

open access: yesFrontiers in Plant Science, 2023
Plant oxylipins are a class of lipid-derived signaling molecules being involved in the regulation of various biotic and abiotic stress responses. A major class of oxylipins are the circular derivatives to which 12-oxo-phytodienoic acid (OPDA) and its ...
Hanno Christoph Resemann   +6 more
doaj   +1 more source

The effect of root hairs on exudate composition: a comparative non-targeted metabolomics approach

open access: yesAnalytical and Bioanalytical Chemistry, 2022
AbstractRoot exudation is a major pathway of organic carbon input into soils. It affects soil physical properties, element solubility as well as speciation, and impacts the microbial community in the rhizosphere. Root exudates contain a large number of primary and secondary plant metabolites, and the amount and composition are highly variable depending
Martin Lohse   +6 more
openaire   +3 more sources

Identification of serum metabolome signatures associated with retinal and renal complications of type 2 diabetes

open access: yesCommunications Medicine, 2023
Tomofuji et al. perform non-targeted metabolomics on serum samples from people with type 2 diabetes with or without complications. The authors identify metabolites associated with retinal and renal complications.
Yoshihiko Tomofuji   +16 more
doaj   +1 more source

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