Results 71 to 80 of about 1,150,684 (289)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Bound states around vacuum in scalar ModMax model

open access: yesPhysics Letters B
In this work, we consider a two-dimensional scalar field model inspired by the dimensional reduction of a four-dimensional ModMax theory. Upon projecting out the 4D theory down to a 2D theory we obtain a theory which presents a constant electric field ...
F.A. Brito   +3 more
doaj   +1 more source

A Fast Parameter Estimation Algorithm for Near-field Non-circular Signals

open access: yesLeida xuebao, 2020
In this paper, a fast parameter estimation algorithm for near-field non-circular signals is proposed, which is based on symmetric, uniform, and linear array, that decouple the near-field steering vector via non-circularity and symmetry.
Jiaqi SONG, Haihong TAO
doaj   +1 more source

A sharp uniform bound for the distribution of sums of Bernoulli trials

open access: yes, 2013
In this note we establish a uniform bound for the distribution of a sum $S_n=X_1+\cdots+X_n$ of independent non-homogeneous Bernoulli trials. Specifically, we prove that $\sigma_n \mathbb{P}(S_n\!=\!j)\leq\eta$ where $\sigma_n$ denotes the standard ...
Alon   +13 more
core   +2 more sources

A non-uniform Datko–Pazy theorem for bounded operator semigroups

open access: yesStudia Mathematica
We present a non-uniform analogue of the classical Datko-Pazy theorem. Our main result shows that an integrability condition imposed on orbits originating in a fractional domain of the generator (as opposed to all orbits) implies polynomial stability of a bounded $C_0$-semigroup.
Paunonen L, Seifert D, Vanspranghe N
openaire   +3 more sources

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

A lower bound for Torelli-K-quasiconformal homogeneity [PDF]

open access: yes, 2014
A closed hyperbolic Riemann surface M is said to be K-quasiconformally homogeneous if there exists a transitive family F of K-quasiconformal homeomorphisms.
Greenfield, Mark
core   +1 more source

Capacitated Center Problems with Two-Sided Bounds and Outliers

open access: yes, 2017
In recent years, the capacitated center problems have attracted a lot of research interest. Given a set of vertices $V$, we want to find a subset of vertices $S$, called centers, such that the maximum cluster radius is minimized. Moreover, each center in
CG Fernandes   +16 more
core   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

Uniform convergence rates for a class of martingales with application in non-linear cointegrating regression

open access: yes, 2014
For a class of martingales, this paper provides a framework on the uniform consistency with broad applicability. The main condition imposed is only related to the conditional variance of the martingale, which holds true for stationary mixing time series,
Chan, Nigel, Wang, Qiying
core   +1 more source

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