Results 71 to 80 of about 428,558 (290)
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Restriction of toral eigenfunctions to hypersurfaces and nodal sets [PDF]
, 2011 We give uniform upper and lower bounds for the L^2 norm of the restriction of eigenfunctions of the Laplacian on the three-dimensional standard flat torus to surfaces with non-vanishing curvature.
Bourgain, Jean, Rudnick, Zeev
core
A default prior for regression coefficients
, 2018 When the sample size is not too small, M-estimators of regression coefficients are approximately normal and unbiased. This leads to the familiar frequentist inference in terms of normality-based confidence intervals and p-values.
van Zwet, Erik
core +1 more source
Non-uniform stability for bounded semi-groups on Banach spaces
Journal of Evolution Equations, 2008 Let S(t) be a bounded strongly continuous semi-group on a Banach space B and – A be its generator. We say that S(t) is semi-uniformly stable when S(t)(A + 1)−1 tends to 0 in operator norm. This notion of asymptotic stability is stronger than pointwise stability, but strictly weaker than uniform stability, and generalizes the known logarithmic ...
Batty, C, Duyckaerts, T
openaire +2 more sources
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Finite-state Strategies in Delay Games (full version)
, 2017 What is a finite-state strategy in a delay game? We answer this surprisingly non-trivial question by presenting a very general framework that allows to remove delay: finite-state strategies exist for all winning conditions where the resulting delay-free ...
Winter, Sarah, Zimmermann, Martin
core +1 more source
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
FEBS Open Bio, EarlyView.Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source
Naked cuticle is essential for Drosophila wing development beyond Wingless signaling
FEBS Open Bio, EarlyView.Naked cuticle (Nkd), a Wnt signaling inhibitor, assumes extensive roles in Drosophila wing development. Overexpressing Nkd causes smaller, crumpled wings, while also perturbing multiple signaling pathways and developmental genes. A specific region (R1S) is critical for Nkd's function as a signaling integrator, offering new insights for studying its ...
Rui Wang, Ping Wang
wiley +1 more source
Non-uniform Berry–Esseen Bounds for Weighted U-Statistics and Generalized L-Statistics [PDF]
Communications in Mathematics and Statistics, 2013 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Hu, Haojun, Shao, Qi-Man
openaire +2 more sources
FEBS Open Bio, EarlyView.Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source