Results 71 to 80 of about 22,626 (299)
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn +4 more
wiley +1 more source
The concept of massive spatial modulation aided multiple-input multiple-output (SM-MIMO) systems, where the base station (BS) is equipped with a large number of antennas and simultaneously serves several multi-antenna users that employ SM for their ...
Longzhuang He +3 more
doaj +1 more source
Uniform entropy and energy bounds for fully non-linear equations [PDF]
Bin Guo, D. H. Phong
openalex +1 more source
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Fundamental Limits of Target Parameter Estimation in OFDM-Based 3D NTN ISAC Systems
This work investigates the fundamental performance bound of three-dimensional (3D) target localization and velocity estimation in monostatic orthogonal frequency-division multiplexing (OFDM)-based ISAC systems equipped with uniform rectangular arrays ...
Luca Arcangeloni +3 more
doaj +1 more source
Some connections between bounded query classes and non-uniform complexity
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Amir, Amihood +2 more
openaire +2 more sources
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley +1 more source
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani +6 more
wiley +1 more source

