Results 111 to 120 of about 187,835 (306)
Mozambican Civil Society Within: Evaluation, Challenges, Opportunities and Action [PDF]
, 2007 The aim of this ambitious venture is to evaluate the main dimensions of civil society's exercise of citizenship: a) its organisational Structure, covering its free and voluntary involvement, participation and contribution to society; b) the socio ...
Albertina Mucavele +3 more
core
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Violence and non-violence in Bonhoeffer's theology
Opuscula Theologica et ScientificaAt 2013 a new debate started about whether Bonhoeffer, who in his mid-twenties turned into a devoted pacifist Christian changed his mind later as agreeing to kill Hitler or stayed a representative of non-violence until his violent death.
András Csepregi
doaj +3 more sources
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Constructing ethnographic relationships: Reflections on key issues and struggles in the field. [PDF]
, 2005 An ethnographer shares his insights from the field about constructing relationships in research. Focusing on a case study in a New Zealand area school, he reflects on his experiences in the field and the key issues he struggled with related to building ...
Cavanagh, Tom
core +1 more source
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Reflections on violence and non violence in the Arab uprisings [PDF]
, 2011 Following the overthrow of the Tunisian and Egyptian presidents in the last two months, the Arab uprisings appear to have stalled. Across the Middle East, the region’s leaders appear to have absorbed the lessons of Tunis and Cairo quickly in order to ...
Barton, Guy
core
Pitie et Non-violence dans 1S 24-26 : Cas de David Versus Saül et Nabal
Old Testament Essays, 2019 This article takes root in the reading of the narrative sequence which we find 1S 24-26 where three narratives follow one after another: at first to David who leads Saul to Engaddi, then to Abigail who diverts David from his plan to avenge Nabal, and ...
Augustin L. Kagunge
doaj +1 more source