Results 101 to 110 of about 5,865,913 (286)

Redefining Fatty Liver Disease: How Updated Nomenclature Reshapes Clinical Laboratory Diagnostics

iLABMED, EarlyView.
The transition from nonalcoholic fatty liver disease (NAFLD) to metabolic dysfunction‐associated steatotic liver disease (MASLD) reorients laboratory diagnosis from exclusion‐based rules toward metabolic and inflammatory biomarkers. This review compares their diagnostic criteria, epidemiology, insulin resistance mechanisms, imaging, and key laboratory ...
Ran Wei, Yuanyue Guan, Meiqing Zhai, Xiuying Zhao   +3 more
wiley   +1 more source

Human biomarker navigator

iMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li, Qian Zhang, Zijie Wang, Zeping Gui, Jing Liu, Jingda Li, Maojun Jiang, Zukang Chang, Qingqing Han, Bendong Yang, Tariq Saeed, Jun Li, Jinghan Jia, Chenghu Song, Tong Shao, Tianhuan Peng, Xueying Zhang, Pingping Guo, Jun Luo, Gangao Yang, Yuan Wan, Gokhan Zengin, Quan Yuan, Lingru Li, Xiaohui Fan, Yang Luo, Lvyun Zhu, Yanfei Zheng, Wenjun Mao, Wenlong Sun   +29 more
wiley   +1 more source

Vaspin mRNA levels in the liver of morbidly obese women with nonalcoholic fatty liver disease [PDF]

, 2017
The aim of this study was to evaluate hepatic vaspin mRNA in morbidly obese women with nonalcoholic fatty liver disease (NAFLD) and to look for its relationships with metabolic and histopathological features.
Grzegorz Kowalski, Tomasz Sawczyn, Paweł Olczyk, Rafał J. Bułdak, Marek Waluga, Dominika Żądło, Ewa Waluga, Michał Dyaczyński, Michał Kukla, Marta Grabiec, Maciej Kajor, Agnieszka Berdowska, Michał Żorniak, Rafał Kotulski, Marek Hartleb   +14 more
core   +1 more source

Adss1–HDAC3 Interaction: A Novel Mechanism for Epigenetic Regulation of Metabolism in Adipose Tissue

iNew Medicine, EarlyView.
ABSTRACT Obesity and its related metabolic disorders have emerged as global public health challenges with underlying mechanisms involving an imbalance between energy storage and expenditure in the adipose tissue. In recent years, with the deepening research on adipose tissue metabolism, the cross talk between metabolic enzymes and epigenetic regulation
Jiarui Zhao, Jingjing Sun, Yan Lu, Ying Yang   +3 more
wiley   +1 more source

Effect of Vitamin D Supplement on Nonalcoholic Fatty Liver: A Systematic Review on Randomized Clinical Trials

تحقیقات نظام سلامت, 2020
Background: Fatty liver is a common metabolic disorder that results in abnormal liver function due to the excessive accumulation of fat in the liver cells. Vitamin D can play a role in the improvement of fatty liver symptoms due to its anti-inflammatory,
فاطمه سادات میریعقوبى, مهران نوری, غلامرضا عسکری   +2 more
doaj  

Assessment and management of comorbidities (including cardiovascular disease) in patients with nonalcoholic fatty liver disease

, 2012
Nonalcoholic fatty liver disease (NAFLD) is the most common cause of liver disease worldwide. Nonalcoholic steatohepatitis, the progressive form of NAFLD, can lead to end‐stage liver disease and hepatocellular carcinoma.
Vuppalanchi, Raj, Corey, Kathleen E.
core   +1 more source

Bisphenol A and Its Analogs: Toxicity Analysis in Mouse and Rat Liver—A Review

Journal of Applied Toxicology, EarlyView.
ABSTRACT Bisphenol A (BPA) and its analogs are widely recognized for their use in industry and plastic manufacturing. Consequently, humans and animals are continually exposed to various substances in their daily lives. This review evaluates the hepatic toxicity of BPA and its analogs in mice and rats, with particular emphasis on molecular mechanisms ...
Sevda Bagdatli, Muhammed Canik, Gizem Gencay, Nurbanu Zengin, Tarık Dinc, Nazan Deniz Yön   +5 more
wiley   +1 more source

Obesity and nonalcoholic fatty liver disease: current perspectives

, 2018
Raiya Sarwar,1 Nicholas Pierce,2 Sean Koppe3 1Department of Internal Medicine, University of Illinois at Urbana-Champaign, Champaign, IL, USA; 2University of Medicine and Health Sciences, New York, NY, USA; 3Department of Medicine, Division of ...
Sarwar R, Pierce N, Koppe S
core  

Organ‐Specific Human Microbiomes and Dysbiosis: Mechanistic Links to Disease and Emerging Therapeutic Strategies

Journal of Clinical Laboratory Analysis, EarlyView.
Schematic overview of the human microbiome and major microbiota‐derived metabolites across body sites, highlighting the gut–brain, gut–heart, and gut–kidney axes in host physiology and disease. ABSTRACT Background The human microbiome is a dynamic and diverse community of microorganisms that affects susceptibility to illness and promotes wellness ...
Awadh Alanazi
wiley   +1 more source

Nonalcoholic fatty liver disease is an early predictor of metabolic diseases in a metabolically healthy population.

PLoS ONE, 2019
AIMS:The relationship between nonalcoholic fatty liver disease and incident metabolic syndrome in metabolically healthy subjects is unknown. We aimed to investigate whether nonalcoholic fatty liver disease is a predictor of future metabolic syndrome in ...
Seokhun Yang, Soongu Kwak, Jeong-Hoon Lee, Shinae Kang, Seung-Pyo Lee   +4 more
doaj   +1 more source