This study demonstrates that equol exerts a protective effect on metabolic dysfunction‐associated steatotic liver disease in both in vivo and in vitro by activating the GPR30/PI3K/Nrf2 signaling pathway. Equol's interaction with GPR30 and its ability to activate the PI3K/Nrf2 pathway provide a promising therapeutic strategy for treating metabolic ...
Hanqiang Cui +8 more
wiley +1 more source
Study on the effect and mechanism of Ershiyiwei Lvronghao concentrated Pills in the treatment of nonalcoholic fatty liver disease. [PDF]
Wu Y +7 more
europepmc +1 more source
Exploring the Gut‐Prostate Axis: Microbial Signatures Linked to Prostate Volume and Bladder Function
ABSTRACT Background Benign prostatic hyperplasia (BPH) is a common urologic condition in aging men, often linked to systemic inflammation and metabolic dysfunction. Emerging evidence suggests that the gut microbiome may contribute to prostate health and disease.
Jonathan Surber +12 more
wiley +1 more source
Examining the mediating effects of metabolic syndrome components on the relationship between dairy product consumption and nonalcoholic fatty liver disease in Korean adults. [PDF]
Jeon H, Kim SH, Shin D.
europepmc +1 more source
ABSTRACT Aims Although the American Diabetes Association (ADA) recently established a diagnostic algorithm for the early detection of liver fibrosis among high‐risk individuals, its implications for chronic kidney disease (CKD) risk stratification remain unclear.
Chan‐Young Jung +4 more
wiley +1 more source
Essential phospholipids and enzyme-based staging in nonalcoholic fatty liver disease: A call to action. [PDF]
Madian A.
europepmc +1 more source
Objective Antinuclear antibodies (ANAs) are present at high titers in 2% of the general population, but their clinical significance in individuals without an autoimmune (AI) disease is not known. We tested the hypothesis that the presence of a high ANA titer in non‐AI conditions is associated with disease.
Matthew Chung +7 more
wiley +1 more source
Association between blood selenium level and nonalcoholic fatty liver disease among naturally menopausal women: A cross-sectional study. [PDF]
Chen C +15 more
europepmc +1 more source
ABSTRACT Extracellular vesicles (EVs) are nanoscale mediators of intercellular communication with diverse molecular cargoes that reflect their cell of origin. Advances in isolation, detection, and single‐particle analytics have revealed increasing molecular and functional heterogeneity, while exposing limitations in how EV identity and activity are ...
David J. Lundy +8 more
wiley +1 more source
Flaxseed oil and probiotics protect against induced nonalcoholic fatty liver disease (NAFLD) in male rats. [PDF]
El Rabey HA +7 more
europepmc +1 more source

