Results 171 to 180 of about 5,888,396 (230)

Assessing the Diagnostic Performance of Triglyceride–Glucose–Based Indices for Early Detection of Metabolic Syndrome in Paediatric Down Syndrome

Journal of Intellectual Disability Research, Volume 70, Issue 10, Page 1022-1032, October 2026.
ABSTRACT Background Down syndrome (DS) youth have an increased risk of metabolic syndrome (MetS). This study assessed the diagnostic performance of the triglyceride–glucose index (TyG) and its derivatives—TyG‐BMI, TyG‐waist circumference (WC) and TyG‐waist‐to‐height ratio (WHtR) in detecting MetS compared with traditional markers.
Valeria Calcaterra, Lucia Labati, Alessandra Anna Gazzarri, Alice De Lorenzo, Ilaria Anna Maria Scavone, Gianvincenzo Zuccotti   +5 more
wiley   +1 more source

Effects of curcumin on anthropometric measurements in nonalcoholic fatty liver disease: An umbrella meta-analysis study. [PDF]

Medicine (Baltimore)
Mahapatro A, Jeanty H, Adla Jala SR, Priya Somu K, Madineni G, Mohanty E, Marsool MD, Shamsi P, Shahriari Namin M, Abbaszadeh S, Saberian P, Amini-Salehi E, Ghazalgoo A.   +12 more
europepmc   +1 more source

Upcoming therapies for steatotic liver disease: Translating breakthroughs into clinical practice

Journal of Internal Medicine, Volume 300, Issue 4, Page 440-460, October 2026.
Abstract Metabolic dysfunction‐associated steatotic liver disease (MASLD) is the most common chronic liver disease worldwide and a leading cause of cirrhosis, hepatocellular carcinoma, and cardiometabolic morbidity. Often clinically silent until advanced fibrosis develops, management has largely relied on lifestyle interventions, with limited ...
Philip N. Newsome, Saima Ajaz
wiley   +1 more source

Impact of nonalcoholic fatty liver disease on the response to pegylated interferon-α therapy in patients with chronic hepatitis B. [PDF]

Microbiol Spectr
Liang H, Xie Y, Dai Y, Yang X, Zheng X, Yang J, Liu Y, Wu C, Chen S, Zhang M, Zhuang H, Lin L, Chen S.   +12 more
europepmc   +1 more source

How Does the Ultra‐Processed Food Industry Drive Consumption Through Product Design and Marketing? Mapping a Complex Commercial System According to Expert Mental Models and Evidence Review

Obesity Reviews, Volume 27, Issue 10, October 2026.
ABSTRACT The corporations that produce and profit from ultra‐processed foods (UPFs), and the regulatory conditions under which they operate, have been major contributors to the global rise of obesity and noncommunicable diseases. The aim was to map the drivers and feedback systems of the product design and marketing domains of the UPF system and to ...
Joshua Clark, Boyd Swinburn, Benjamin Wood, Gary Sacks, Kim Anastasiou, Penelope Milsom, Phillip Baker, Kelly Garton   +7 more
wiley   +1 more source

Dietary Inflammatory Index and risk of nonalcoholic fatty liver disease: nonlinear associations, metabolic mediation, and external validation. [PDF]

Front Nutr
Chen T, Zheng G, Tan H, Guo L, Liu Y, Qian X, Feng S, Zhang Y.   +7 more
europepmc   +1 more source

Metformin Inhibits Trophoblast Ferroptosis by Suppressing ATF2 and Activating the PI3K/Akt/Nrf2 Pathway to Improve Gestational Diabetes Mellitus

The FASEB Journal, Volume 40, Issue 18, 30 September 2026.
Metformin suppresses ATF2 expression, activating the PI3K/Akt pathway and promoting Nrf2 nuclear translocation. This upregulates GPX4, inhibiting ferroptosis in trophoblast cells. Erastin blocks system Xc−, depleting GSH and promoting ferroptosis. LY294002 and ML385 inhibit the pathway, validating the mechanism.
Dandan Xia, Yuhui Zhang, Wenjie Liu, Siyu Li, Chenying Zhang, Guangtong She, Huiyan Wang   +6 more
wiley   +1 more source

Identification of Gene Signatures and Molecular Mechanisms for Diagnosing Parkinson's Disease and Nonalcoholic Fatty Liver Disease Using Machine Learning. [PDF]

Parkinsons Dis
Chen X, Wu Y, Zhang Y, Hou Y.
europepmc   +1 more source

Nonalcoholic fatty liver disease assessed by multiple tools are correlated to periodontal conditions. [PDF]

Sci Rep
Hiroshimaya T, Iwai K, Marutani M, Azuma T, Yonenaga T, Tabata K, Watanabe K, Deguchi F, Obora A, Kojima T, Tomofuji T, Tamaki N.   +11 more
europepmc   +1 more source

m1A Epitranscriptomic Control of NUPR1 by YTHDF1 Exacerbates Metabolic Dysregulation in Nonalcoholic Fatty Liver Disease. [PDF]

J Clin Transl Hepatol
Luo N, Xu Z, Zhao D, Yang X, Tian Y, Li R.   +5 more
europepmc   +1 more source