Results 251 to 260 of about 94,246 (299)

Evaluation of Pathogenic Variants Associated With Monogenic Disorders of Dyslipidemia in Patients With Well Characterised MASLD

open access: yesLiver International, Volume 46, Issue 2, February 2026.
ABSTRACT Background and Aims Dyslipidemia is common in patients with MASLD, but the frequency and significance of inherited disorders of dyslipidemia are unclear. We investigated the prevalence and significance of pathogenic variants associated with selected monogenic disorders of dyslipidemia in 3358 patients with well‐characterised MASLD. Approach We
Tae‐Hwi Schwantes‐An   +12 more
wiley   +1 more source

Gpx4 Deletion‐Mediated Macrophage Ferroptosis Alleviates Obesity‐Associated Insulin Resistance

open access: yesThe FASEB Journal, Volume 40, Issue 2, 31 January 2026.
Macrophage‐specific loss of Gpx4 induces ferroptosis, thereby alleviating high‐fat diet (HFD)‐induced obesity, insulin resistance, and metabolic dysfunction, and conferring systemic metabolic protection in type 2 diabetes (T2D). ABSTRACT Obesity has become a global epidemic and a major contributor to the development of Type 2 diabetes (T2D) through the
Suhua Wu   +13 more
wiley   +1 more source

Engineered Hydrogels for Organoid Models of Human Nonalcoholic Fatty Liver Disease. [PDF]

open access: yesAdv Sci (Weinh)
Liu Y   +11 more
europepmc   +1 more source

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