Results 51 to 60 of about 122,669 (246)

Alcoholic, Nonalcoholic, and Toxicant-Associated Steatohepatitis: Mechanistic Similarities and DifferencesSummary

Cellular and Molecular Gastroenterology and Hepatology, 2015
Hepatic steatosis and steatohepatitis are common histologic findings that can be caused by multiple etiologies. The three most frequent causes for steatosis/steatohepatitis are alcohol (alcoholic steatohepatitis, ASH), obesity/metabolic syndrome ...
Swati Joshi-Barve, Irina Kirpich, Matthew C. Cave, Luis S. Marsano, Craig J. McClain   +4 more
doaj   +1 more source

Cenicriviroc Treatment for Adults With Nonalcoholic Steatohepatitis and Fibrosis: Final Analysis of the Phase 2b CENTAUR Study

Hepatology, 2020
Cenicriviroc (CVC) is a C‐C chemokine receptors type 2 and 5 dual antagonist under evaluation for treating liver fibrosis in adults with nonalcoholic steatohepatitis (NASH).
V. Ratziu, A. Sanyal, S. Harrison, V. Wong, S. Francque, Z. Goodman, G. Aithal, K. Kowdley, S. Seyedkazemi, L. Fischer, R. Loomba, M. Abdelmalek, F. Tacke   +12 more
semanticscholar   +1 more source

Role of Neutrophils in the Pathogenesis of Nonalcoholic Steatohepatitis

Frontiers in Endocrinology, 2021
Nonalcoholic fatty liver disease (NAFLD) includes a spectrum of liver disorders, from fatty liver to nonalcoholic steatohepatitis (NASH), cirrhosis, and hepatocellular carcinoma.
Seonghwan Hwang, Hwayoung Yun, S. Moon, Y. Cho, Bin Gao   +4 more
semanticscholar   +1 more source

Relationship of sarcopenia with steatohepatitis and advanced liver fibrosis in non-alcoholic fatty liver disease: a meta-analysis

BMC Gastroenterology, 2018
Background Several studies have emerged indicating that sarcopenia is associated with nonalcoholic fatty liver disease, we aimed to systematically review and quantify the association between sacropenia and the histological severity of nonalcoholic fatty ...
Rui Yu, Qiangwei Shi, Lei Liu, Lidong Chen   +3 more
doaj   +1 more source

THE EFFECT OF BICYCLOL ON THE STATE OF THE CONNECTIVE TISSUE COMPONENTS OF THE LIVER EXTRACELLULAR MATRIX IN THE COMPLEX THERAPY OF NON-ALCOHOLIC STEATOHEPATITIS WITH LIVER FIBROSIS IN PATIENTS WITH TYPE 2 DIABETES MELLITUS

Східноукраїнський медичний журнал, 2021
The aim of the research was to determine the probable effect of metformin, rosuvastatin and bicyclol on markers of hepatocyte cytolysis in patients with nonalcoholic steatohepatitis and diabetes mellitus type 2 with diabetic kidney disease, the degree of
Zorіana Ya. Kotsіubiіchuk, Oksana S. Khukhlina, Aliona A. Antonіv, Oleksandra I. Roshchuk, Olga Ye. Mandryk, Oleksandra V. Garvasіuk   +5 more
doaj   +1 more source

Nonalcoholic steatohepatitis is the second leading etiology of liver disease among adults awaiting liver transplantation in the United States.

Gastroenterology, 2015
BACKGROUND & AIMS Nonalcoholic steatohepatitis (NASH) has been predicted to become the leading indication for liver transplantation (LT) in the United States.
R. Wong, M. Aguilar, R. Cheung, R. Perumpail, S. Harrison, Z. Younossi, Aijaz Ahmed   +6 more
semanticscholar   +1 more source

EFFECT OF HELICOBACTER PYLORI ERADICATION ON HEPATIC STEATOSIS, NAFLD FIBROSIS SCORE AND HSENSI IN PATIENTS WITH NONALCOHOLIC STEATOHEPATITIS: a MR imaging-based pilot open-label study

Arquivos de Gastroenterologia, 2014
Context Limited clinical data suggest Helicobacter pylori (Hp) infection may contribute to nonalcoholic fatty liver disease (NAFLD) pathogenesis. Objectives The effect of Hp eradication on hepatic steatosis (magnetic resonance imaging), nonalcoholic ...
Stergios A POLYZOS, Panagiotis NIKOLOPOULOS, Angeliki STOGIANNI, Iordanis ROMIOPOULOS, Panagiotis KATSINELOS, Jannis KOUNTOURAS   +5 more
doaj   +1 more source

CAQ Corner: Basic concepts of transplant immunology

, 2022
Liver Transplantation, EarlyView.
Amanda Cheung, Josh Levitsky
wiley   +1 more source

Formyl peptide receptor 2 determines sex-specific differences in the progression of nonalcoholic fatty liver disease and steatohepatitis

Nature Communications, 2022
Prevalence of nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH) higher in men than premenopausal women. Here the authors report that formyl peptide receptor 2 (FPR2) levels are regulated by estrogen, and that FPR2 ...
Chanbin Lee, Jieun Kim, Jinsol Han, Dayoung Oh, Minju Kim, Hayeong Jeong, Tae-Jin Kim, Sang-Woo Kim, Jeong Nam Kim, Young-Su Seo, Ayako Suzuki, Jae Ho Kim, Youngmi Jung   +12 more
doaj   +1 more source

CAQ Corner: Immune‐mediated complications

, 2022
Liver Transplantation, EarlyView.
Mary Thomson, John R. Lake
wiley   +1 more source