Results 51 to 60 of about 101,002 (279)

Treatment of nonalcoholic fatty liver disease with dapagliflozin in non-diabetic patients

Metabolism Open, 2020
Steatosis, a condition characterized by excessive lipid deposition. Although usually a benign condition, steatosis mays progress to cirrhosis or hepatocellular carcinoma.
Lucas Ribeiro dos Santos, MSc., Ricardo Baer Filho   +1 more
doaj   +1 more source

Synergistic interaction of fatty acids and oxysterols impairs mitochondrial function and limits liver adaptation during nafld progression [PDF]

, 2018
The complete mechanism accounting for the progression from simple steatosis to steatohepatitis in nonalcoholic fatty liver disease (NAFLD) has not been elucidated.
Avolio, Carlo, Bellanti, Francesco, Blonda, Maria, di Bello, Giorgia, Facciorusso, Antonio, Iannelli, Giuseppina, Iuliano, Luigi, Poli, Giuseppe, Serviddio, Gaetano, Tamborra, Rosanna, Vendemiale, Gianluigi, Villani, Rosanna   +11 more
core   +2 more sources

Nonalcoholic steatohepatitis and hepatocellular carcinoma: Brazilian survey

Clinics, 2016
OBJECTIVE: The majority of cases of hepatocellular carcinoma have been reported in individuals with cirrhosis due to chronic viral hepatitis and alcoholism, but recently, the prevalence has become increasingly related to nonalcoholic steatohepatitis ...
Helma P. Cotrim, Claudia P. Oliveira, Henrique Sérgio M. Coelho, Mario R. Alvares-da-Silva, Leticia Nabuco, Edison Roberto Parise, Claúdia Ivantes, Ana LC Martinelli, João Galizzi-Filho, Flair J. Carrilho   +9 more
doaj   +1 more source

Viability assessment and transplantation of fatty liver grafts using end‐ischemic normothermic machine perfusion

Liver Transplantation, EarlyView., 2022
Abstract End‐ischemic viability testing by normothermic machine perfusion (NMP) represents an effective strategy to recover liver grafts having initially been discarded for liver transplantation (LT). However, its results in the setting of significant (≥30%) macrovesicular steatosis (MaS) have not been specifically assessed.
Damiano Patrono, Riccardo De Carlis, Alessandro Gambella, Francesca Farnesi, Alice Podestà, Andrea Lauterio, Francesco Tandoi, Luciano De Carlis, Renato Romagnoli   +8 more
wiley   +1 more source

Relationship of sarcopenia with steatohepatitis and advanced liver fibrosis in non-alcoholic fatty liver disease: a meta-analysis

BMC Gastroenterology, 2018
Background Several studies have emerged indicating that sarcopenia is associated with nonalcoholic fatty liver disease, we aimed to systematically review and quantify the association between sacropenia and the histological severity of nonalcoholic fatty ...
Rui Yu, Qiangwei Shi, Lei Liu, Lidong Chen   +3 more
doaj   +1 more source

Reduced expression of chemerin in visceral adipose tissue associates with hepatic steatosis in patients with obesity [PDF]

, 2016
Objective: This study aimed to evaluate whether circulating levels and/or visceral adipose tissue (VAT) expression of recently described adipokines associate with histopathological severity of nonalcoholic fatty liver disease (NAFLD), independent of ...
Alfadda, Behari, Bekaert, Bozaoglu, Brunt, Bugianesi, Chakaroun, Deng, Docke, Donnelly, Ehrlund, Fuster, Greulich, Gruben, Haukeland, Heiker, Kanda, Kim, Kleiner, Luangsay, Mahdi, Marchesini, Musso, Ouwens, Polyzos, Polyzos, Rivera, Saxena, Seki, Sell, Sell, Souza Batista, Wittamer, Wittamer, Wolfs, Wong, Yang, Yilmaz, Zelber-Sagi, Zeng   +39 more
core   +1 more source

Alcoholic, Nonalcoholic, and Toxicant-Associated Steatohepatitis: Mechanistic Similarities and DifferencesSummary

Cellular and Molecular Gastroenterology and Hepatology, 2015
Hepatic steatosis and steatohepatitis are common histologic findings that can be caused by multiple etiologies. The three most frequent causes for steatosis/steatohepatitis are alcohol (alcoholic steatohepatitis, ASH), obesity/metabolic syndrome ...
Swati Joshi-Barve, Irina Kirpich, Matthew C. Cave, Luis S. Marsano, Craig J. McClain   +4 more
doaj   +1 more source

THE EFFECT OF BICYCLOL ON THE STATE OF THE CONNECTIVE TISSUE COMPONENTS OF THE LIVER EXTRACELLULAR MATRIX IN THE COMPLEX THERAPY OF NON-ALCOHOLIC STEATOHEPATITIS WITH LIVER FIBROSIS IN PATIENTS WITH TYPE 2 DIABETES MELLITUS

Східноукраїнський медичний журнал, 2021
The aim of the research was to determine the probable effect of metformin, rosuvastatin and bicyclol on markers of hepatocyte cytolysis in patients with nonalcoholic steatohepatitis and diabetes mellitus type 2 with diabetic kidney disease, the degree of
Zorіana Ya. Kotsіubiіchuk, Oksana S. Khukhlina, Aliona A. Antonіv, Oleksandra I. Roshchuk, Olga Ye. Mandryk, Oleksandra V. Garvasіuk   +5 more
doaj   +1 more source

Cell-free DNA methylation as liquid biopsy for the assessment of fibrosis in patients with nonalcoholic steatohepatitis: a gap between innovation and implementation [PDF]

, 2017
The presence of cfDNA in the circulating compartment was demonstrated three decades ago , leading to the emergence of liquid biopsy.However, the implementation of cfDNA methylation as a non-invasive molecular tool for the diagnosis of fibrosis imposes ...
Pirola, Carlos José, Sookoian, Silvia Cristina   +1 more
core   +1 more source

Nonalcoholic Steatohepatitis

Seminars in Liver Disease, 1999
Nonalcoholic steatohepatitis (NASH) is an hepatic disorder with histologic features of alcohol-induced liver disease that occurs in individuals who do not consume significant alcohol. NASH is believed to be one of the most common explanations for abnormal liver chemistries in American adults.
  +7 more sources