Results 81 to 90 of about 122,669 (246)
Hepatology, 2020 Nonalcoholic steatohepatitis (NASH) is a common cause of chronic liver disease. Clinical trials use the NASH Clinical Research Network (CRN) system for semiquantitative histological assessment of disease severity.
Feng Liu +18 more
semanticscholar +1 more source
Management and Modification of Flavonoids Against Nonalcoholic Fatty Liver Disease
Food Bioengineering, EarlyView.Flavonoids protect against NAFLD by enhancing mitochondrial function, reducing ER stress, and modulating gut microbiota. Structural modifications improve flavonoid efficacy, offering a promising dietary strategy for NAFLD management. ABSTRACT Flavonoids are small bioactive molecules commonly found in plant‐derived foods, exhibiting antioxidant, anti ...
Weidong Bai +6 more
wiley +1 more source
Crosstalk Between Liver Macrophages and Surrounding Cells in Nonalcoholic Steatohepatitis
Frontiers in Immunology, 2020 Nonalcoholic steatohepatitis (NASH), the advanced stage of nonalcoholic fatty liver disease (NAFLD), is emerging as a leading cause of progressive liver fibrosis and end-stage liver disease.
Hai-ou Li +8 more
semanticscholar +1 more source
Food Frontiers, EarlyView.Ganoderic acid A (GA) improved lipid metabolism disorders by inhibiting intestinal FXR. GA markedly suppressed the ileal intestinal FXR activity. Then, GA changed bile acid composition and upregulated hepatic Cyp7a1 mRNA through decreasing FXR target genes encoded protein levels.
Feng Lu +7 more
wiley +1 more source
Cell Death and Disease, 2019 Nonalcoholic steatohepatitis (NASH) is a metabolic liver disease that progresses from simple steatosis to the disease state of inflammation and fibrosis.
Shinya Tsurusaki +11 more
semanticscholar +1 more source
PENYAKIT PERLEMAKAN HATI NON ALKOHOLIK PADA ANAK
Majalah Kedokteran Andalas, 2012 AbstrakPenyakit perlemakan hati nonalkoholik (NAFLD) ditandai dengan penumpukan lemak di hati pada penderita yang tidak mengkonsumsi alkohol sebelumnya, meliputi steatosis sederhana dan steatohepatitis nonalkoholik (NASH).
Yusri Dianne Jurnalis +2 more
doaj +1 more source
Nonalcoholic fatty liver disease
Annals of Hepatology, 2004 Nonalcoholic fatty liver disease is a clinicopathologic syndrome that encompasses several clinical entities. The spectrum of conditions ranges from simple steatosis to steatohepatitis, fibrosis and end stage liver disease.
Lafaine M. Grant, Mauricio Lisker-Melman
doaj +1 more source
Development of a novel machine learning model to predict presence of nonalcoholic steatohepatitis [PDF]
, 2021 Matt Docherty +10 more
openalex +1 more source
The metabolic basis of nonalcoholic steatohepatitis
Endocrinology, Diabetes & Metabolism, 2020 Nonalcoholic fatty liver disease (NAFLD) is a major cause of chronic liver disease and is associated with significant morbidity and mortality worldwide, with a high incidence in Western countries and non‐Western countries that have adopted a Western diet.
M. Chakravarthy, B. Neuschwander‐Tetri
semanticscholar +1 more source
Potential role of thymosin beta 4 in the treatment of nonalcoholic fatty liver disease
Chronic Diseases and Translational Medicine, 2017 As a result of increased prevalence of obesity worldwide, non-alcoholic fatty liver disease (NAFLD) has become one of the most common causes of chronic liver disease. Although most NAFLD cases remain benign, some progress to end-stage liver diseases such
Yong Jiang +6 more
doaj +1 more source