Results 41 to 50 of about 9,424,993 (263)
FEBS Open Bio, EarlyView.Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata +3 more
wiley +1 more source
AxiomsThis article highlights the oscillatory properties of second-order Emden–Fowler delay differential equations featuring sublinear neutral terms and multiple delays, encompassing both canonical and noncanonical cases. Through the proofs of several theorems,
Ahmed Alemam +4 more
doaj +1 more source
A novel hypomorphic splice variant in EIF2B5 gene is associated with mild ovarioleukodystrophy
Annals of Clinical and Translational Neurology, 2020 Objective To identify the genetic cause in an adult ovarioleukodystrophy patient resistant to diagnosis. Methods We applied whole‐exome sequencing (WES) to a vanishing white matter disease patient associated with premature ovarian failure at 26 years of ...
Agustí Rodríguez‐Palmero +11 more
doaj +1 more source
The fourth order strongly noncanonical operators
, 2018 It is shown that the strongly noncanonical fourth order ...
Baculikova Blanka, Dzurina Jozef
core +1 more source
Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells
FEBS Open Bio, EarlyView.Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla +10 more
wiley +1 more source
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
Aging and Cancer, EarlyView.This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
, 2022 Supplementary Figure from Pharmacologic Reduction of Mitochondrial Iron Triggers a Noncanonical BAX/BAK-Dependent Cell ...
Kevin Tran (519050) +28 more
core +3 more sources
β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations
Advanced Biology, Volume 9, Issue 3, March 2025.Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio +11 more
wiley +1 more source
Advanced Functional Materials, EarlyView.Versatile guanosine‐quadruplex (GQ) hydrogels are developed as dynamic biomatrices for cell culture. These scaffolds are fabricated under mild aqueous conditions, present improved stability, tunable mechanical properties within physiological ranges; fibrillar, porous microstructure, ion conductivity, and cytocompatibility.
Neha Thakur +10 more
wiley +1 more source
COMPACT REPRESENTATION OF THE PRIORITY MATRIX WITH HIGH DIMENSIONALITY [PDF]
Научно-технический вестник информационных технологий, механики и оптики, 2015 We propose methods for compact representation of priority matrix with high dimensionality, which is used to describe priority queueing disciplines of demands in systems with nonhomogeneous load.
T. I. Aliev
doaj +1 more source