Results 61 to 70 of about 9,424,993 (263)

Investigations of the Evolved Molecular Basis for Terpenoid Biosynthesis in Marine Sponges

open access: yesAdvanced Science, EarlyView.
Confirming and extending a previous observation in another Bubarida sponge, genomic and functional analyses of A. cavernosa reveal that sponges retain the mevalonate pathway and employ single α‐domain T1TSs and UbiA‐type TSs for terpenoid biosynthesis. The absence of T1TSs clustering with other biosynthetic genes tentatively suggests, based on limited ...
Fangyan Chen   +6 more
wiley   +1 more source

New Oscillation Results for Second-Order Advanced Differential Equations with Mixed Neutral Nonlinearities

open access: yesAxioms
This paper investigates the oscillatory behavior of a new class of second-order nonlinear neutral advanced differential equations with mixed superlinear and sublinear neutral terms in the noncanonical case.
Zuhur Alqahtani   +3 more
doaj   +1 more source

Noncanonical LALR(1) Parsing

open access: yes, 2005
This paper addresses the longstanding problem of the recognition limitations of classical LALR(1) parser generators by proposing the usage of noncanonical parsers. To this end, we present a definition of noncanonical LALR(1) parsers, NLALR(1).
Sylvain Schmitz
core   +1 more source

Selective Modulation of OTUB1 Noncanonical Function via a bioPhosTAC Strategy

open access: yesAdvanced Science, EarlyView.
This work positions the versatile performance of the peptide‐based bioPhosTAC platform for dissecting phosphorylation‐dependent biology and expanding the scope of induced‐proximity technologies. We demonstrated that selective manipulation of a tyrosine phosphorylation site is sufficient to propagate coordinated cellular consequences.
Seung Un Seo   +7 more
wiley   +1 more source

Noncanonical DNA-binding proteins: from identification to next generation peptide-based anticancer therapeutics

open access: yes, 2020
Background: G-quadruplexes and i-motifs are biologically relevant noncanonical DNA secondary structures, whose existence in vivo has been unambiguously demonstrated by their visualization in human cells.
bruno pagano
core  

Quantitative Live-cell Reporter Assay for Noncanonical Wnt Activity

open access: yes, 2018
Noncanonical Wnt signaling functions independently of the β-catenin pathway to control diverse developmental processes, and dysfunction of the pathway contributes to a number of human pathological conditions, including birth defects and metastatic cancer.
Edith Karuna   +6 more
core   +1 more source

Exploring the noncanonical translatome using massively integrated coexpression analysis

open access: yes, 2023
This is supplementary data files for the publication entitled "Massively integrated coexpression analysis reveals transcriptional regulation, evolution and cellular implications of the noncanonical translatome"
Omer Acar (11938058)   +2 more
core   +1 more source

Targeting the PHB2–ACSL3 Lipid‐Remodeling Axis Overcomes Cisplatin Resistance by Restoring Ferroptosis in Gastric Cancer

open access: yesAdvanced Science, EarlyView.
ABSTRACT Platinum‐based chemotherapy resistance remains a major obstacle in gastric cancer (GC) treatment. Through integrated transcriptomic profiling of cisplatin‐resistant xenografts and pharmacogenomic interrogation of the NCI‐60 dataset, we identified Prohibitin‐2 (PHB2) as a previously unrecognized determinant of chemoresistance.
Liang Xu   +10 more
wiley   +1 more source

Noncanonical Hamiltonian Formulation of Ideal Magnetohydrodynamics [PDF]

open access: yes, 1982
A noncanonical Poisson structure for ideal magnetohydrodynamics is presented and identified with a differential Lie ...
Kupershmidt, B. A., Holm, D. D.
core  

Noncanonical Wnt signaling in vertebrate development, stem cells, and diseases

open access: yes, 2010
Wnt signaling regulates many aspects of vertebrate development and adult stem cells. Deregulation of Wnt signaling causes development defect and cancer. The signaling is categorized in two pathways: canonical and noncanonical. Both pathways are initiated
Li, Linheng   +3 more
core   +1 more source

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