Results 71 to 80 of about 2,277,128 (298)

Noncommunicable diseases are the leading cause of death worldwide.

, 2023
(A) Proportion of worldwide deaths attributable to noncommunicable diseases (NCDs), communicable or infectious diseases, and injuries through time. (B) Proportion of deaths within the USA in 2019, broken down by the top 10 causes of death.
Christopher D. Golden (7431806), Samuel S. Urlacher (9192894), Ian J. Wallace (16965092), Daniel E. Lieberman (16965095), Donald Mogoi (16965089), Andrew G. Clark (8569380), Julien F. Ayroles (10580370), Andrew W. Dahl (9243673), Dino J. Martins (3641653), Thomas S. Kraft (3255267), Päivi Pajukanta (62537), Herman Pontzer (148534), Michael Gurven (112946), Angela R. Garcia (9359202), George H. Perry (8039960), Benjamin C. Trumble (9359199), Vivek V. Venkataraman (5098868), Orrin Devinsky (356636), Yvonne A. L. Lim (8129274), Amanda J. Lea (11790137), Joseph Kamau (218679)   +20 more
core   +1 more source

A Facial Foundation Model for Clinical Biomarker Prediction and Real‐World Mobile Deployment

Advanced Science, EarlyView.
MedicalFaceFound is a facial foundation model developed through three‐stage progressive pre‐training, adapting representations from general vision to facial structure and clinical phenotypes. Using a single facial image, it estimates 62 biomarkers across multiple physiological systems and supports downstream risk prediction for cardiovascular ...
Tingfeng Xu, Huixuan Xu, Li Lin, Fei Wang, Yaodong Ding, Shuangqiao Liao, Xingyu Chen, Jichen Wen, Hongqiang Zhao, Jing Hao, Weixiang Zhao, Gong Zhang, Shiguang Shan, Yong Zeng, Hu Han, Minxian Wang   +15 more
wiley   +1 more source

NS1‐Induced PARP1 Phase Transitions Prolongs Host Transcriptional Pausing to Promote Influenza A Virus Replication

Advanced Science, EarlyView.
After IAV infection, NS1 induces PARP1 phase transition, reducing molecular mobility in condensates, prolonging host transcriptional pause, aiding RdRp cap snatching, and promoting viral transcription. ABSTRACT Influenza A virus (IAV) commandeers host transcriptional machinery to replicate, but mechanisms remain elusive.
Shufeng Ma, Changyuan Kang, Xixian Liu, Lichao Yang, Mengyi Li, Yuting Ye, Jianfang Zhang, Yingjun Li, Guanghui Jin, Yang Liu, Xiaohong Chen, Kexin Wang, Zifeng Yang   +12 more
wiley   +1 more source

A Multi‐Targeting Chimeric Antigen Receptor‐T Cell Platform to Overcome Antigen Heterogeneity in the Treatment of Non‐Small Cell Lung Cancer

Advanced Science, EarlyView.
A dual‐transmembrane Bicephali CAR‐T platform simultaneously targets CD276 and NKG2D ligands to address antigen heterogeneity in non‐small cell lung cancer. By improving immune synapse formation, mitochondrial fitness, antioxidant capacity, and stem‐like persistence, this design enhances durable tumor control and provides a versatile strategy to ...
Lina Wang, Yanlei Zhang, Shuixiu Peng, Chenchen Hou, Huaqi Guo, Tianyu Zhou, Alex H. Chang, Lifeng Yan, Weining Xiong   +8 more
wiley   +1 more source

Prevalence and predictors of high blood pressure among postmenopausal women in Bangladesh

Discover Public Health
Background In Bangladesh, there is limited evidence on prevalence of high blood pressure (HBP) and its risk factors among postmenopausal women (PMW).
Lingkan Barua, Fardina Rahman Omi, Rijwan Bhuiyan, Muhammed Shahriar Zaman, Mithila Faruque, Muhammad Aziz Rahman   +5 more
doaj   +1 more source

Transformer‐Based Multitask Framework Integrating Habitat and Deep Learning for Predicting Early Disease Control and Survival in Immunotherapy‐Treated Hepatocellular Carcinoma

Advanced Science, EarlyView.
This study developed ECOS‐Net, a transformer‐based multitask framework integrating CT‐derived habitat and 2.5D deep learning features to simultaneously predict early disease control and overall survival in hepatocellular carcinoma patients treated with immune checkpoint inhibitors.
Xiaona Fu, Yusheng Guo, Bingxin Gong, Jie Lou, Ning Wang, Xuejun Chen, Hongtao Hu, Rundong Wang, Xiaofang Guo, Shanmei Li, Yangyang Xie, Shichao Long, Mengsi Li, Shubo Pan, Wen Shen, Zhaogang Zhang, Zifang Song, Pengchen Liang, Xiaoyun Liang, Peng Sun, Guilin Zhang, Shanshan Jiang, Jinxiang Zhang, Lian Yang   +23 more
wiley   +1 more source

Multisector Strategy in Addressing Noncommunicable Diseases in the Philippines [PDF]

, 2013
This report is a continuation of the discussion paper of the Philippine Institute for Development Studies entitled "Inequalities in Noncommunicable Diseases in the Philippines".
Aldeon, Melanie P., Ulep, Valerie Gilbert T., dela Cruz, Nina Ashley O.   +2 more
core  

Alkylating Agent–Induced FANCL Impairment Damages Pulmonary Arterial, Venous, and Microvascular Endothelial Cells and Predisposes to PAH/PVOD

Advanced Science, EarlyView.
This study establishes a novel cisplatin‐induced rat model of PAH/PVOD and identifies a conserved mechanistic axis—FANCL impairment, DNA damage accumulation, and endothelial dysfunction—triggered by cisplatin or mitomycin C across pulmonary arteries, veins, and microvessels.
Shiyun Liu, Yufei Sun, Xinlei Wu, Haixia Chen, Shaocong Mo, Zichong Li, Yiwei Gong, Xiaoqian Shan, Yuanqi Li, Yaru Guan, Junqi Zhu, Han Yan, Min Du, Feng Wei, Peixin Ou, Ziyi Wang, Chenting Zhang, Lei Xu, Wenju Lu, Jian Wang, Kai Yang   +20 more
wiley   +1 more source

Encouraging tobacco control using national multisectoral ministerial mandate and priorities in Indonesia

Tobacco Induced Diseases, 2018
Background and challenges to implementation Indonesia remains as one of the highest tobacco consuming countries. While there is intention by Ministry of Health to bring tobacco control as national multi-sectoral priority; still there is a need to find ...
Farrukh Qureshi, Dina Kania
doaj   +1 more source

Vienna Declaration on nutrition and noncommunicable diseases in the context of Health 2020Vienna, Austria 4–5 July 2013

, 2013
4 p.At the WHO Ministerial Conference on Nutrition and Noncommunicable Diseases in the Context of Health 2020, held in Vienna, Austria, 4–5 July 2013, ministers of health, key partners and experts met to face the challenges posed by the burden and threat
WHO Ministerial Conference on Nutrition and Noncommunicable Diseases in the Context of Health 2020, World Health Organization. Regional Office for Europe   +1 more
core