Results 201 to 210 of about 532,604 (238)
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Plasma nonesterified fatty acids in pregnancy
American Journal of Obstetrics and Gynecology, 1960Abstract 1. The effect of various combinations of glucose and insulin on plasma NEFA concentrations were tested in normal pregnant, early puerperal, and nonpregnant subjects. 2. The responses observed in plasma NEFA were dependent upon the amount of glucose administered as well as the time of glucose loading in relation to that of insulin ...
Richard L. Burt, Richard L. Burt
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High-Throughput Quantitative Lipidomics Analysis of Nonesterified Fatty Acids in Human Plasma.
Journal of Proteome Research, 2016We present a high-throughput, nontargeted lipidomics approach using liquid chromatography coupled to high-resolution mass spectrometry for quantitative analysis of nonesterified fatty acids.
Nicolas Christinat +2 more
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Hepatology, 2020
Obesity‐induced pathogenesis of nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH) is associated with increased de novo lipogenesis (DNL) and hepatic glucose production (HGP) that is due to excess fatty acids.
S. Steensels +9 more
semanticscholar +1 more source
Obesity‐induced pathogenesis of nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH) is associated with increased de novo lipogenesis (DNL) and hepatic glucose production (HGP) that is due to excess fatty acids.
S. Steensels +9 more
semanticscholar +1 more source
The Significance of Nonesterified Fatty Acids in Plasma
Archives of Internal Medicine, 1958Recent studies have clarified some aspects of fatty acid transport. The results promise to be of clinical importance, since fat, as a major energy source and as a component of body structure, plays a central role in chronic diseases of metabolism. For example, obesity can be conceived as an abnormal balance between the total amount of fatty acid stored
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Cellular Transport of Nonesterified Fatty Acids
Journal of Molecular Neuroscience, 2001Transport of nonesterified fatty acids (NEFA) is an important component of whole-body energy metabolism, and derangements in NEFA transport have been linked to several diseases. NEFA are transferred from their sites of production to cells in hepatic and peripheral tissues by mechanisms that are regulated in part by cell status and as determined by the ...
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Sensitive micro determination of nonesterified fatty acids
Microchemical Journal, 1972Abstract A procedure is described in which an extremely sensitive copper ligand, TETD, is used as a substitute for DDC in the indirect determination of NEFA. The latter was isolated by extraction into chloroform as a copper soap followed by reaction between TETD and the copper in acid solution.
Adam Manasterski, R. Watkins, Bennie Zak
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Effect of nonesterified fatty acids on the stability of prostacyclin activity
Metabolism, 1983The half-life of the platelet antiaggregatory activity of prostacyclin (PGI2) is prolonged when PGI2 is incubated in human plasma or in fatty-acid-free human albumin solutions. This "PGI2-protective" effect is diminished when fatty acids are added to the incubate, and the diminution is proportional to the concentration of the nonesterified fatty acids ...
Alice M. Mikhailidis +3 more
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Nonesterified fatty acids in the pathogenesis of hypertension: theory and evidence
Prostaglandins, Leukotrienes and Essential Fatty Acids, 1997This paper approaches the hypothesis that fatty acids contribute to hypertension by examining possible interactions of nonesterified fatty acids with renal pressure-natriuresis, peripheral vascular resistance, and the central nervous barostat, three loci where long-term regulation of blood pressure is probably controlled.
Theodore L. Goodfriend +3 more
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Accumulation of nonesterified fatty acids in ischemic canine myocardium
American Journal of Physiology-Heart and Circulatory Physiology, 1984In ischemic myocardium the time course of nonesterified fatty acid (NEFA) accumulation was studied in relation to changes in regional metabolism and mechanics. In open-chest dogs a coronary artery was partially occluded for 120 min. In the ischemic myocardium no increase was observed in NEFA content within 10 min, whereas changes were found in ...
Will A. Coumans +5 more
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Mechanisms of interference of nonesterified fatty acids in radioimmunoassays of steroids
Clinica Chimica Acta, 1979Addition of nonesterified fatty acids caused an apparent increase in unbound steroid present in supernatants in radioimmunoassays for steroids utilizing dextran-coated charcoal. Nonesterified fatty acid interference occurred at the initial binding interaction between steroid and its antiserum, and also at the step separating bound from unbound steroid.
Judith M. Rash +2 more
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