Results 211 to 220 of about 532,604 (238)
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Nonesterified fatty acids and endothelial dysfunction
International Congress Series, 2003Nonesterified fatty acids (NEFA) induce vascular effects, such as the inhibition of insulin-induced nitric oxide (NO) production. In small arteries, relaxation is largely NO-independent. We aimed to assess the effect of elevated NEFA on NO-independent vasodilation. Protocols were performed before and after 120 min of a lipid emulsion infusion.
AVOGARO, ANGELO +3 more
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Mono‐ and polyenoic acid distribution in plasma nonesterified fatty acids in Kwashiorkor
Lipids, 1971AbstractPlasma NEFA levels were determined in Kwashiorkor (17 cases) and normal infants (13 cases) by Dole's method. The distribution of mono‐ and polyenoic acids was investigated by Abdel‐Wahab's method. Plasma NEFA levels were found to be significantly lower in Kwashiorkor infants (445 μEq/L±32) than in normals (591 μEq/L±66).
F. Abdel-Wahab +5 more
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The effect of nonesterified fatty acids and progesterone on bupivacaine protein binding
Clinical Pharmacology and Therapeutics, 1986We examined the influence of elevations in levels of nonesterified fatty acids (NEFAs) and progesterone concentrations on bupivacaine protein binding. The addition of NEFAs to isolated binding proteins of bupivacaine (alpha 1-acid glycoprotein and serum albumin) resulted in an increased binding to alpha 1-acid glycoprotein and an inconsistent decrease ...
Dennis E. Coyle +3 more
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Nonesterified fatty acids in blood pressure control and cardiovascular complications
Current Hypertension Reports, 2001The fact that cardiovascular risk factors cluster among individuals with the insulin resistance syndrome strongly suggests a common pathogenetic denominator. For many years, abnormalities of nonesterified fatty acid metabolism have been implicated in the disturbances of carbohydrate and lipid metabolism that characterize the cluster.
Theodore L. Goodfriend +2 more
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Analytical Chemistry, 2018
High-throughput screening methods for fatty acid (FA) determination are urgently needed due to their critical biochemical roles in human health while serving as biomarkers of habitual diet and chronic disease risk assessment.
S. Azab, Ritchie Ly, P. Britz‐McKibbin
semanticscholar +1 more source
High-throughput screening methods for fatty acid (FA) determination are urgently needed due to their critical biochemical roles in human health while serving as biomarkers of habitual diet and chronic disease risk assessment.
S. Azab, Ritchie Ly, P. Britz‐McKibbin
semanticscholar +1 more source
Nonesterified fatty acids modulate steroidogenesis in mouse Leydig cells
American Journal of Physiology-Endocrinology and Metabolism, 1989The effects of nonesterified fatty acids (NEFA) in modulating testosterone synthesis stimulated by luteinizing hormone (LH, 10 ng/sample) were investigated in isolated adult mouse Leydig cells. LH-stimulated testosterone production was inhibited by triglycerides (0-500 mg/dl, 50 mg/dl, 94% of the control and 500 mg/dl, 40%) and by a mixture of NEFA ...
W. D. Boam +4 more
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American Journal of Physiology, 1960
Catheters placed in the portal and hepatic veins of dogs were maintained in position for 2–4 weeks, and experiments were performed in the unanesthetized state no less than 3 days after the operative procedure. Hepatic uptake of nonesterified fatty acids (
M. Fine, R. H. Williams
semanticscholar +1 more source
Catheters placed in the portal and hepatic veins of dogs were maintained in position for 2–4 weeks, and experiments were performed in the unanesthetized state no less than 3 days after the operative procedure. Hepatic uptake of nonesterified fatty acids (
M. Fine, R. H. Williams
semanticscholar +1 more source
Assay of Serum Nonesterified Fatty Acids by Atomic Absorption Spectrophotometry
American Journal of Clinical Pathology, 1973Assay of nonesterified fatty acids in 100 μ l. of serum is described. The fatty acids are extracted with chloroform-heptane-methanol solvent, and their copper complexes are determined by atomic absorption spectrophotometry. This technic possesses the sensitivity (20 μ moles per 1.) and reliability (4.2% coefficient of variation) required for clinical ...
Derek P. Lehane, Mario Werner
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Nonesterified Fatty Acids and Development of Graft Failure in Renal Transplant Recipients
Transplantation, 2013Chronic transplant dysfunction is the most common cause of graft failure on the long term. Proteinuria is one of the cardinal clinical signs of chronic transplant dysfunction. Albumin-bound fatty acids (FA) have been hypothesized to be instrumental in the etiology of renal damage induced by proteinuria.
Henri G. D. Leuvenink +7 more
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Effects of Nonesterified Fatty Acids on Glucose Metabolism After Glucose Ingestion
Diabetes, 1997Impaired suppression of plasma nonesterified fatty acids (NEFAs) after glucose ingestion may contribute to glucose intolerance, but the mechanisms are unclear. Evidence that insulin inhibits hepatic glucose output (HGO), in part by suppressing plasma NEFA levels, suggests that impaired suppression of plasma NEFA after glucose ingestion would impair HGO
Joseph G. Yu +4 more
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