Results 11 to 20 of about 111,518 (268)

Comparison of Chromosomal Microarray Analysis and Noninvasive Prenatal Testing in Pregnant Women with Fetal Ultrasonic Soft Markers. [PDF]

Risk Manag Healthc Policy
Objective This study aimed to assess the utility of chromosomal microarray analysis (CMA) and noninvasive prenatal testing (NIPT) in detecting clinically significant chromosomal abnormalities among fetuses presenting ultrasonic soft markers (USMs ...
Hu X, Hu Y, Wang H, Yu C, Zheng J, Zhang H, Zheng J.   +6 more
europepmc   +2 more sources

Application of ultrasound combined with noninvasive prenatal testing in prenatal testing. [PDF]

Transl Pediatr, 2022
Both noninvasive prenatal testing (NIPT) and prenatal ultrasound are widely used in clinical settings due to their safety, noninvasiveness, and accuracy, showing high detection rates for fetal chromosomal aneuploidies and structural abnormalities.
Liu C, Zhou Y, Liu P, Geng Y, Zhang H, Dun Y, Zhen M, Zhao Z, Zhu M, Huang Q, Liu R, Wang X.   +11 more
europepmc   +4 more sources

Clinical evaluation of noninvasive prenatal testing for sex chromosome aneuploidies in 9,176 Korean pregnant women: a single-center retrospective study. [PDF]

BMC Pregnancy Childbirth
Background To evaluate the clinical significance of noninvasive prenatal testing (NIPT) for detecting fetal sex chromosome aneuploidies (SCAs) in Korean pregnant women.
Kim H, Park JE, Kang KM, Jang HY, Go M, Yang SH, Kim JC, Lim SY, Cha DH, Choi J, Shim SH.   +10 more
europepmc   +2 more sources

Clinical experience of noninvasive prenatal testing for rare chromosome abnormalities in singleton pregnancies. [PDF]

Front Genet, 2022
Objectives: The study aimed to investigate the clinical use of noninvasive prenatal testing (NIPT) for common fetal aneuploidies as a prenatal screening tool for the detection of rare chromosomal abnormalities (RCAs). Methods: Gravidas with positive NIPT
Hu T, Wang J, Zhu Q, Zhang Z, Hu R, Xiao L, Yang Y, Liao N, Liu S, Wang H, Niu X, Liu S.   +11 more
europepmc   +2 more sources

Positive predictive value of noninvasive prenatal testing for sex chromosome abnormalities. [PDF]

Mol Biol Rep, 2022
Early and intermediate serological screening cannot detect sex chromosome abnormalities. Currently, noninvasive prenatal testing (NIPT) is the only procedure available for screening such disorders; however, its use is controversial.
Guo N, Cai M, Lin M, Xue H, Huang H, Xu L.   +5 more
europepmc   +2 more sources

Efficiency of expanded noninvasive prenatal testing in the detection of fetal subchromosomal microdeletion and microduplication in a cohort of 31,256 single pregnancies. [PDF]

Sci Rep, 2022
Noninvasive prenatal testing (NIPT) is widely used to screen for common fetal chromosomal aneuploidies. However, the ability of NIPT-Plus to detect copy number variation (CNV) is debatable.
Xue H, Yu A, Lin M, Chen X, Guo Q, Xu L, Huang H.   +6 more
europepmc   +2 more sources

The accuracy and feasibility of noninvasive prenatal testing in a consecutive series of 20,626 pregnancies with different clinical characteristics. [PDF]

J Clin Lab Anal, 2022
To evaluate the accuracy and feasibility of noninvasive prenatal testing (NIPT) according to the results of NIPT and pregnancy outcomes with different indications.
Zheng Y, Li J, Zhang J, Yang H.
europepmc   +2 more sources

Attitudes of Filipino parents of children with Down syndrome on noninvasive prenatal testing. [PDF]

J Community Genet, 2022
Globally, there has been an increasing uptake of noninvasive prenatal testing (NIPT). In the Philippines, the test is currently available through private laboratories and can be availed by families who can afford the out-of-pocket cost.
de Castro-Hamoy LG, Tumulak MJR, Cagayan MSFS, Sy PA, Mira NRC, Laurino MY.   +5 more
europepmc   +2 more sources

Health economic evaluation of noninvasive prenatal testing and serum screening for down syndrome. [PDF]

PLoS One, 2022
Background Down syndrome (DS), also known as trisomy 21 (T21), is the most common genetic disorder associated with intellectual disability. There are two methods commonly used for prenatal testing of DS: serum screening (SS) for biomarkers in maternal ...
Xiao G, Zhao Y, Huang W, Hu L, Wang G, Luo H.   +5 more
europepmc   +2 more sources

Hierarchical Classification of Factors Associated With Noninvasive Prenatal Testing Failures and Its Impact on Pregnancy Outcomes [PDF]

Maternal-Fetal Medicine
. Objective. To conduct a hierarchical classification analysis of the nonreportable results of noninvasive prenatal testing in an attempt to reduce failure rates and provide pregnant women with accurate information to alleviate their anxiety. Methods. In
Yang Pan, Jue Li, Jieqiong Xie, Yu Jiang, Yulin Zhou, Dandan Jin, Xingxiu Lu, Yunsheng Ge   +7 more
doaj   +2 more sources