Results 51 to 60 of about 111,518 (268)

Noninvasive Prenatal Paternity Testing (NIPAT) through Maternal Plasma DNA Sequencing: A Pilot Study. [PDF]

PLoS ONE, 2016
Short tandem repeats (STRs) and single nucleotide polymorphisms (SNPs) have been already used to perform noninvasive prenatal paternity testing from maternal plasma DNA.
Haojun Jiang, Yifan Xie, Xuchao Li, Huijuan Ge, Yongqiang Deng, Haofang Mu, Xiaoli Feng, Lu Yin, Zhou Du, Fang Chen, Nongyue He   +10 more
doaj   +1 more source

Non-invasive prenatal testing (NIPT): is routinization problematic?

BMC Medical Ethics, 2023
Background The introduction and wide application of non-invasive prenatal testing (NIPT) has triggered further evolution of routines in the practice of prenatal diagnosis.
Christoph Rehmann-Sutter, Daniëlle R. M. Timmermans, Aviad Raz   +2 more
doaj   +1 more source

Noninvasive prenatal diagnosis of 21-Hydroxylase deficiency using target capture sequencing of maternal plasma DNA. [PDF]

, 2017
Here, we aimed to validate a noninvasive method using capture sequencing for prenatal diagnosis of congenital adrenal hyperplasia due to 21-Hydroxylase deficiency (21-OHD).
Asan, Chen, Chao, Cheng, Jian, Guo, Fengyu, Hu, Ping, Jiang, Tao, Luo, Chunyu, Ma, Dingyuan, Sun, Yun, Wang, Jian, Wang, Wei, Wang, Yaoshen, Xu, Zhengfeng, Yang, Huanming, Yi, Xin, Yuan, Yuan, Zhang, Jingjing   +16 more
core   +2 more sources

The Emergence and Global Spread of Noninvasive Prenatal Testing.

Annual review of genomics and human genetics (Print), 2021
Since its introduction in 2011, noninvasive prenatal testing (NIPT) has spread rapidly around the world. It carries numerous benefits but also raises challenges, often related to sociocultural, legal, and economic contexts.
V. Ravitsky, Marie-Christine Roy, Hazar Haidar, L. Henneman, J. Marshall, A. Newson, Olivia M Y Ngan, Tamar Nov-Klaiman   +7 more
semanticscholar   +1 more source

Complete Androgen Insensitivity Syndrome: A Rare Case of Prenatal Diagnosis

Revista Brasileira de Ginecologia e Obstetrícia, 2021
With the widespread uptake of noninvasive prenatal testing (NIPT), a larger cohort of women has access to fetal chromosomal sex, which increases the potential to identify prenatal sex discordance. The prenatal diagnosis of androgen insensitivity syndrome
Maria Liz Coelho, Elisa Soares, Marília Freixo, Pedro Brandão, Carla Marinho, Juliana Rocha, Graça Rodrigues   +6 more
doaj   +1 more source

Prenatal ultrasound screening for fetal anomalies and outcomes in high-risk pregnancies due to maternal HIV infection : a retrospective study [PDF]

, 2013
Objective: To assess the prevalence of prenatal screening and of adverse outcome in high-risk pregnancies due to maternal HIV infection. Study design: The prevalence of prenatal screening in 330 pregnancies of HIV-positive women attending the ...
Buxmann, Horst, Haberl, Annette Elisabeth, Herrmann, Eva, Louwen, Frank, Reitter, Anke, Schlößer, Rolf Lambert, Stücker, Anja-Undine   +6 more
core   +2 more sources

Noninvasive prenatal testing from cell-free DNA [PDF]

Canadian Medical Association Journal, 2014
For references, please see Appendix 1, available at [www.cmaj.ca/lookup/suppl/doi:10.1503/cmaj.131551/-/DC1][1] The test analyzes fragments of DNA derived from the placenta circulating in maternal blood.
Christine M, Armour, Sarah M, Nikkel
openaire   +2 more sources

Noninvasive prenatal testing: limitations and unanswered questions [PDF]

Genetics in Medicine, 2014
The clinical use of noninvasive prenatal testing to screen high-risk patients for fetal aneuploidy is becoming increasingly common. Initial studies have demonstrated high sensitivity and specificity, and there is hope that these tests will result in a reduction of invasive diagnostic procedures as well as their associated risks.
Monica A, Lutgendorf, Katie A, Stoll, Dana M, Knutzen, Lisa M, Foglia   +3 more
openaire   +2 more sources

Assessment and Clinical Utility of a Non-Next-Generation Sequencing-Based Non-Invasive Prenatal Testing Technology

Current Issues in Molecular Biology, 2021
Background: Rolling-circle replication (RCR) is a novel technology that has not been applied to cell-free DNA (cfDNA) testing until recently. Given the cost and simplicity advantages of this technology compared to other platforms currently used in cfDNA ...
Uzay Gormus, Alka Chaubey, Suresh Shenoy, Yong Wee Wong, Lee Yin Chan, Bao Ping Choo, Liza Oraha, Anna Gousseva, Fredrik Persson, Lawrence Prensky, Ephrem Chin, Madhuri Hegde   +11 more
doaj   +1 more source

Development of a comprehensive noninvasive prenatal test [PDF]

Genetics and Molecular Biology, 2018
Our aim was to develop and apply a comprehensive noninvasive prenatal test (NIPT) by using high-coverage targeted next-generation sequencing to estimate fetal fraction, determine fetal sex, and detect trisomy and monogenic disease without parental genotype information.
Malcher, Carolina, Yamamoto, Guilherme L., Burnham, Philip, Ezquina, Suzana A.M., Lourenço, Naila C.V., Balkassmi, Sahilla, Antonio, David S. Marco, Hsia, Gabriella S.P., Gollop, Thomaz, Pavanello, Rita C., Lopes, Marco Antonio, Bakker, Egbert, Zatz, Mayana, Bertola, Débora, Vlaminck, Iwijn De, Passos-Bueno, Maria Rita   +15 more
openaire   +6 more sources