Results 41 to 50 of about 1,264,156 (319)

Nonlinear DNA dynamics: Nonlinearity versus dispersion [PDF]

Applied Mathematics and Computation, 2013
In the present paper we study the impact of dispersion and nonlinearity on DNA dynamics. We rely on the helicoidal Peyrard-Bishop model and use the fact that nonlinear DNA dynamics represents an interplay between nonlinearity and dispersion. We state that a dispersion coefficient and a coefficient of nonlinearity, existing in nonlinear Schrödinger ...
Slobodan Zdravkovic, Miljko V. Sataric
openaire   +3 more sources

Bell Polynomials Approach Applied to (2 + 1)-Dimensional Variable-Coefficient Caudrey-Dodd-Gibbon-Kotera-Sawada Equation

Abstract and Applied Analysis, 2014
The bilinear form, bilinear Bäcklund transformation, and Lax pair of a (2 + 1)-dimensional variable-coefficient Caudrey-Dodd-Gibbon-Kotera-Sawada equation are derived through Bell polynomials. The integrable constraint conditions on variable coefficients
Wen-guang Cheng, Biao Li, Yong Chen
doaj   +1 more source

Broadband Mid-IR Light Sources From Difference Frequency Generators Based on a 2-mm-Long Aperiodically-Poled Lithium-Niobate Crystal

IEEE Photonics Journal, 2021
We present a difference frequency generator (DFG) based on a 2-mm-long MgO-doped aperiodically-poled lithium-niobate (APPLN) crystal with a linearly-varying poling-period.
Xi Feng, Fang Liu, Chengxiao Ning, Jinqiao Shi, Pei Liu, Jiaxing Heng, Zhaowei Zhang   +6 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Application of fractional sub-equation method to nonlinear evolution equations [PDF]

, 2018
In this paper, we constructed a traveling wave solutions expressed by three types of functions, which are hyperbolic, trigonometric, and rational functions.
Abdelkawy, Mohamed A. A., Biswas, Anjan, Al-Denari, Rasha B. B., El-Kalaawy, Omar H. H.   +3 more
core   +2 more sources

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Existence and uniqueness of solutions for a singular system of higher-order nonlinear fractional differential equations with integral boundary conditions [PDF]

, 2013
In this paper, we study the existence and uniqueness of solutions for a singular system of nonlinear fractional differential equations with integral boundary conditions.
Lu, Xinyi, Wang, Lin, Zhang, Xingqiu
core   +2 more sources

High-contrast and reversible scattering switching via hybrid metal-dielectric metasurfaces

Beilstein Journal of Nanotechnology, 2018
Novel types of optical hybrid metasurfaces consist of metallic and dielectric elements are designed and proposed for controlling the interference between magnetic and electric modes of the system, in a reversible manner.
Jonathan Ward, Khosro Zangeneh Kamali, Lei Xu, Guoquan Zhang, Andrey E. Miroshnichenko, Mohsen Rahmani   +5 more
doaj   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Existence and uniqueness of positive solutions for a class of nonlinear fractional differential equations with mixed-type boundary value conditions [PDF]

, 2018
In this article, we study a class of nonlinear fractional differential equations with mixed-type boundary conditions. The fractional derivatives are involved in the nonlinear term and the boundary conditions. By using the properties of the Green function,
Kong, Debin, Wang, Fang, Wu, Yonghong, Liu, Lishan   +3 more
core   +2 more sources