Results 51 to 60 of about 1,258,536 (319)

Mid-infrared Suspended Membrane Waveguide and Ring Resonator on Silicon-on-Insulator

open access: yesIEEE Photonics Journal, 2012
Theoretical and experimental studies of mid-infrared (mid-IR) suspended membrane waveguide (SMW) and suspended membrane ring (SMR) resonator are presented.
Zhenzhou Cheng   +4 more
doaj   +1 more source

Dynamical Networks Modelling Applied to Low Voltage Lines with Nonlinear Filters

open access: yesApplied System Innovation, 2020
The nonlinear dynamical behaviour of a network that is submitted to disturbances is the starting point of this work, where we consider a low voltage line (the network) with nonlinear varistor filters responding, dynamically, to those disturbances ...
Mauro Fazion Filho
doaj   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

open access: yesMolecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi   +14 more
wiley   +1 more source

Parabolic Nonlinear Second Order Slip Reynolds Equation: Approximation and Existence

open access: yes, 2007
This work studies an initial boundary value problem for nonlinear degenerate parabolic equation issued from a lubrication slip model. Existence of solutions is established through a semi discrete scheme approximation combined with some a priori&
Ait Hadi, K.
core   +1 more source

Epilepsy Diagnosis Analysis via a Multiple-Measures Composite Strategy from the Viewpoint of Associated Network Analysis Methods

open access: yesApplied Sciences
Based on some typical complex network analysis methods and machine learning techniques, a general multiple-measures composited strategy-guided epilepsy diagnosis analysis framework is proposed in this brief paper.
Haoying Niu   +4 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

On the optimality of some multi-point methods for finding multiple roots of nonlinear equation

open access: yes, 2016
This paper deals with the problem of determining the multiple roots of nonlinear equations, where the multiplicity of the roots is known. The paper contains some remarks on the optimality of the recently published methods [B. Liu, X.
Ralević, Nebojša M. M., Ćebić, Dejan
core   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

Global Stability and Exponential Decay of Processes in Nonlinear Feedback Systems with Different Fractional Orders

open access: yesJ, 2021
The global stability of continuous-time multi-input multi-output nonlinear feedback systems with different fractional orders and interval matrices of positive linear parts is investigated.
Tadeusz Kaczorek, Łukasz Sajewski
doaj   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

open access: yesFEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake   +4 more
wiley   +1 more source

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