Results 51 to 60 of about 2,761,221 (299)

Instability and dynamics of two nonlinearly coupled laser beams in a plasma [PDF]

, 2006
We investigate the nonlinear interaction between two laser beams in a plasma in the weakly nonlinear and relativistic regime. The evolution of the laser beams is governed by two nonlinear Schroedinger equations that are coupled with the slow plasma ...
Dieckmann, M. E., Eliasson, B., Kourakis, I., Marklund, M., Parviainen, M., Shukla, P. K., Stenflo, L.   +6 more
core   +3 more sources

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Epilepsy Diagnosis Analysis via a Multiple-Measures Composite Strategy from the Viewpoint of Associated Network Analysis Methods

Applied Sciences
Based on some typical complex network analysis methods and machine learning techniques, a general multiple-measures composited strategy-guided epilepsy diagnosis analysis framework is proposed in this brief paper.
Haoying Niu, Tiange Mu, Yuting Wang, Jiayang Huang, Jie Liu   +4 more
doaj   +1 more source

Mid-infrared Suspended Membrane Waveguide and Ring Resonator on Silicon-on-Insulator

IEEE Photonics Journal, 2012
Theoretical and experimental studies of mid-infrared (mid-IR) suspended membrane waveguide (SMW) and suspended membrane ring (SMR) resonator are presented.
Zhenzhou Cheng, Xia Chen, Chi Yan Wong, Ke Xu, Hon Ki Tsang   +4 more
doaj   +1 more source

Dynamical Networks Modelling Applied to Low Voltage Lines with Nonlinear Filters

Applied System Innovation, 2020
The nonlinear dynamical behaviour of a network that is submitted to disturbances is the starting point of this work, where we consider a low voltage line (the network) with nonlinear varistor filters responding, dynamically, to those disturbances ...
Mauro Fazion Filho
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Nonlinear DNA dynamics: Nonlinearity versus dispersion [PDF]

Applied Mathematics and Computation, 2013
In the present paper we study the impact of dispersion and nonlinearity on DNA dynamics. We rely on the helicoidal Peyrard-Bishop model and use the fact that nonlinear DNA dynamics represents an interplay between nonlinearity and dispersion. We state that a dispersion coefficient and a coefficient of nonlinearity, existing in nonlinear Schr dinger ...
Zdravković, Slobodan, Satarić, Miljko V.   +1 more
openaire   +3 more sources

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Large nonlinear Kerr effect in graphene

, 2012
Under strong laser illumination, few-layer graphene exhibits both a transmittance increase due to saturable absorption and a nonlinear phase shift.
Bao, Qiaoliang, Godbout, Nicolas, Kockaert, Pascal, Loh, Kian Ping, Massar, Serge, Virally, Stephane, Zhang, Han   +6 more
core   +1 more source

Dynamics of modulationally unstable ionacoustic wave packets in plasmas with negative ions [PDF]

, 2008
In this paper we study the propagation of nonlinear ion-acoustic waves in plasmas with negative ions. The Gardner equation governing these waves in plasmas with the negative ion concentration close to critical is derived.
Berezin, Das, Das, Das, EFIM PELINOVSKY, Engelbrecht, Grimshaw, Lonngren, MICHAEL S. RUDERMAN, Tagare, TATYANA TALIPOVA   +10 more
core   +1 more source