Results 31 to 40 of about 157,302 (264)

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

open access: yesFEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang   +7 more
wiley   +1 more source

Cooperative Passivity-Based Control of Nonlinear Mechanical Systems

open access: yesRobotics, 2023
In this work, we propose two cooperative passivity-based control methods for networks of mechanical systems. By cooperatively synchronizing the end-effector coordinates of the individual agents, we achieve cooperation between systems of different types ...
Oscar de Groot   +2 more
doaj   +1 more source

Tracking Control for Nonlinear Networked Control Systems [PDF]

open access: yesIEEE Transactions on Automatic Control, 2014
We investigate the tracking control of nonlinear networked control systems (NCS) affected by disturbances. We consider a general scenario in which the network is used to ensure the communication between the controller, the plant and the reference system generating the desired trajectory to be tracked.
Postoyan, R   +3 more
openaire   +3 more sources

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

open access: yesFEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu   +5 more
wiley   +1 more source

Nonlinear Control Systems Simulation Using Spreadsheets

open access: yesSpreadsheets in Education, 2004
In this paper, a method for simulating nonlinear control systems using spreadsheets is presented. Various nonlinear blocks are simulated using graphics and cell formulas, and are generated by clicking on specially developed toolbar buttons.
Ali El-Hajj   +2 more
doaj  

Design of a multivariable neural controller for control of a nonlinear MIMO plant

open access: yesInternational Journal of Applied Mathematics and Computer Science, 2014
The paper presents the training problem of a set of neural nets to obtain a (gain-scheduling, adaptive) multivariable neural controller for control of a nonlinear MIMO dynamic process represented by a mathematical model of Low-Frequency (LF) motions of a
Bańka Stanisław   +2 more
doaj   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

open access: yesFEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake   +4 more
wiley   +1 more source

Prediction of Myasthenia Gravis Worsening: A Machine Learning Algorithm Using Wearables and Patient‐Reported Measures

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is a rare disorder characterized by fluctuating muscle weakness with potential life‐threatening crises. Timely interventions may be delayed by limited access to care and fragmented documentation. Our objective was to develop predictive algorithms for MG deterioration using multimodal telemedicine data ...
Maike Stein   +7 more
wiley   +1 more source

Enhanced precision in robot arm positioning: A nonlinear damping approach for flexible joint manipulators

open access: yesIET Control Theory & Applications
This article introduces an advanced nonlinear controller designed for optimizing the performance of a single‐link robot arm featuring a flexible joint.
Amir Hossein Jafari   +2 more
doaj   +1 more source

Optimal Control of Nonlinear Multivariable Systems [PDF]

open access: yesIranian Journal of Chemistry & Chemical Engineering, 2009
This paper concerns a study on the optimal control for nonlinear systems. An appropriate alternative in order to alleviate the nonlinearity of a system is the exact linearization approach.
Ali Qajar   +1 more
doaj  

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