Results 41 to 50 of about 988,791 (345)

Control of nonlinear underactuated systems

open access: yes, 1999
In this paper we introduce a new method to design control laws for non-linear underactuated systems. Our method produces an infinite dimensional family of control laws, whereas most control techniques only produce a finite dimensional family.
Auckly, Dave   +2 more
core   +2 more sources

State dependent NGMV control of delayed piecewise affine systems [PDF]

open access: yes, 2009
A Nonlinear Generalized Minimum Variance (NGMV) control algorithm is introduced for the control of delayed piecewise affine (PWA) systems which are an important subclass of hybrid systems.
Grimble, M.J., Pang, Y.
core   +2 more sources

Nonsquare Spectral Factorization for Nonlinear Control Systems [PDF]

open access: yes, 2005
This paper considers nonsquare spectral factorization of nonlinear input affine state space systems in continuous time. More specifically, we obtain a parametrization of nonsquare spectral factors in terms of invariant Lagrangian submanifolds and ...
Petersen, Mark A.,   +1 more
core   +2 more sources

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Adaptive control of nonlinear underwater robotic systems [PDF]

open access: yesModeling, Identification and Control, 1991
The problem of controlling underwater mobile robots in 6 degrees of freedom (DOF) is addressed. Uncertainties in the input matrix due to partly known nonlinear thruster characteristics are modeled as multiplicative input uncertainty.
Thor I. Fossen, Svein I. Sagatun
doaj   +1 more source

Controlled invariance for nonlinear systems: Two worked examples [PDF]

open access: yesIEEE Transactions on Automatic Control, 1984
In recent years a (local) nonlinear version of the theory of (A,B)- invariant subspaces has been developed, under suitable regularity conditions, by Hirschhorn, Isidori, Krener, Nijmeijer and van der Schaft. The purpose of the present paper is to illustrate the existing theory by two worked examples. The first example deals with the dynamics of a rigid
Nijmeijer, Henk, van der Schaft, Arjan
openaire   +2 more sources

Mathematical control of complex systems 2013 [PDF]

open access: yes, 2014
Mathematical control of complex systems have already become an ideal research area for control engineers, mathematicians, computer scientists, and biologists to understand, manage, analyze, and interpret functional information/dynamical behaviours from ...
Dong, H   +5 more
core   +4 more sources

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Generalized Controlled Invariance for Nonlinear Systems [PDF]

open access: yesSIAM Journal on Control and Optimization, 1997
Summary: A general setting is developed which describes controlled invariance for nonlinear control systems and which incorporates the previous approaches dealing with controlled invariant (co -) distributions. A special class of controlled invariant subspaces, called controllability cospaces, is introduced.
Huijberts, Henri   +2 more
openaire   +3 more sources

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

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