Results 61 to 70 of about 226,681 (319)

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Enhanced precision in robot arm positioning: A nonlinear damping approach for flexible joint manipulators

IET Control Theory & Applications
This article introduces an advanced nonlinear controller designed for optimizing the performance of a single‐link robot arm featuring a flexible joint.
Amir Hossein Jafari, Rached Dhaouadi, Reza Jafari   +2 more
doaj   +1 more source

Optimal Control of Nonlinear Multivariable Systems [PDF]

Iranian Journal of Chemistry & Chemical Engineering, 2009
This paper concerns a study on the optimal control for nonlinear systems. An appropriate alternative in order to alleviate the nonlinearity of a system is the exact linearization approach.
Ali Qajar, Ramin Bozorgmehry Boozarjomehry,   +1 more
doaj  

Realization of multivariable nonlinear systems via the approaches of differential forms and differential algebra

, 2010
summary:In this paper differential forms and differential algebra are applied to give a new definition of realization for multivariable nonlinear systems consistent with the linear realization theory.
Moog, Claude H., Moog, Claude, Xia, Xiaohua, Moog, Claude, H., Zhang, Jiangfeng, Zhang, Jiangfeng Jeff   +5 more
core   +1 more source

Necessary optimality conditions for Lagrange problems involving ordinary control systems described by fractional Laplace operators

, 2020
In this paper, optimal control problems containing ordinary nonlinear control systems described by fractional Dirichlet and Dirichlet–Neumann Laplace operators and a nonlinear integral performance index are studied. Using smooth-convex maximum principle,
Kamocki, Rafał
core   +1 more source

Brainstem and Cerebellar Volume Loss and Associated Clinical Features in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Progressive Supranuclear Palsy (PSP) is a neurodegenerative ‘tauopathy’ with predominating pathology in the basal ganglia and midbrain. Caudal tau spread frequently implicates the cerebellum; however, the pattern of atrophy remains equivocal.
Chloe Spiegel, Timothy P. Siejka, Cassandra Marotta, Josh J. Y. Lee, Kelly Bertram, Terence J. O'Brien, Meng Law, Lucy Vivash, Ian H. Harding   +8 more
wiley   +1 more source

Controlled invariance for nonlinear systems: Two worked examples [PDF]

IEEE Transactions on Automatic Control, 1984
In recent years a (local) nonlinear version of the theory of (A,B)- invariant subspaces has been developed, under suitable regularity conditions, by Hirschhorn, Isidori, Krener, Nijmeijer and van der Schaft. The purpose of the present paper is to illustrate the existing theory by two worked examples. The first example deals with the dynamics of a rigid
Nijmeijer, Henk, van der Schaft, Arjan
openaire   +2 more sources

Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher, Charles B. Malpas, Stuart J. McDonald, William T. O’Brien, Craig Despott, Kelly L. Bertram, Matthew P. Pase, Lukas Frontzkowski, Meng Law, Terence J. O’Brien, Lucy Vivash   +10 more
wiley   +1 more source

$\mathcal {H}_{2}$- and $\mathcal {H}_\infty$-Optimal Model Predictive Controllers for Robust Legged Locomotion

IEEE Open Journal of Control Systems
This paper formally develops robust optimal predictive control solutions that can accommodate disturbances and stabilize periodic legged locomotion.
Abhishek Pandala, Aaron D. Ames, Kaveh Akbari Hamed   +2 more
doaj   +1 more source

Adaptive NN output-feedback control for stochastic time-delay nonlinear systems with unknown control coefficients and perturbations

, 2016
This paper addresses the problem of adaptive output-feedback control for more general class of stochastic time-varying delay nonlinear systems with unknown control coefficients and perturbations.
Duan, Na, Min, Hui Fang Fang
core   +1 more source