Results 51 to 60 of about 988,791 (345)

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

open access: yesFEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake   +4 more
wiley   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Cooperative Passivity-Based Control of Nonlinear Mechanical Systems

open access: yesRobotics, 2023
In this work, we propose two cooperative passivity-based control methods for networks of mechanical systems. By cooperatively synchronizing the end-effector coordinates of the individual agents, we achieve cooperation between systems of different types ...
Oscar de Groot   +2 more
doaj   +1 more source

An Information-state based Approach to the Optimal Output Feedback Control of Nonlinear Systems [PDF]

open access: green, 2021
Raman Goyal   +4 more
openalex   +1 more source

Tracking Control for Nonlinear Networked Control Systems [PDF]

open access: yesIEEE Transactions on Automatic Control, 2014
We investigate the tracking control of nonlinear networked control systems (NCS) affected by disturbances. We consider a general scenario in which the network is used to ensure the communication between the controller, the plant and the reference system generating the desired trajectory to be tracked.
Postoyan, R   +3 more
openaire   +3 more sources

GMV control of nonlinear multivariable systems [PDF]

open access: yes, 2004
A Generalized Minimum Variance control law is derived for the control of nonlinear, possibly time-varying multivariable systems. The solution for the control law is original and was obtained in the time-domain using a simple operator representation of ...
Grimble, M.J.
core  

Recent advances on filtering and control for nonlinear stochastic complex systems with incomplete information: A survey [PDF]

open access: yes, 2012
This Article is provided by the Brunel Open Access Publishing Fund - Copyright @ 2012 Hindawi PublishingSome recent advances on the filtering and control problems for nonlinear stochastic complex systems with incomplete information are surveyed.
Liang, J, Liu, Y, Shen, B, Wang, Z
core   +3 more sources

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky   +8 more
wiley   +1 more source

Nonlinear Control Systems Simulation Using Spreadsheets

open access: yesSpreadsheets in Education, 2004
In this paper, a method for simulating nonlinear control systems using spreadsheets is presented. Various nonlinear blocks are simulated using graphics and cell formulas, and are generated by clicking on specially developed toolbar buttons.
Ali El-Hajj   +2 more
doaj  

Design of a multivariable neural controller for control of a nonlinear MIMO plant

open access: yesInternational Journal of Applied Mathematics and Computer Science, 2014
The paper presents the training problem of a set of neural nets to obtain a (gain-scheduling, adaptive) multivariable neural controller for control of a nonlinear MIMO dynamic process represented by a mathematical model of Low-Frequency (LF) motions of a
Bańka Stanisław   +2 more
doaj   +1 more source

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