Results 41 to 50 of about 1,370,774 (268)

Statistical Inference for Partially Observed Markov Processes via the R Package pomp [PDF]

, 2015
Partially observed Markov process (POMP) models, also known as hidden Markov models or state space models, are ubiquitous tools for time series analysis.
Ionides, Edward L., King, Aaron A., Nguyen, Dao   +2 more
core   +4 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Estimation of lactation curves of Gyr cattle and some associated production parameters in the Colombian low tropic

Revista Colombiana de Ciencias Pecuarias, 2021
Background: The Gyr breed is widely used in Colombian low tropic dairy production systems. During the last 10 years, the Asociación Colombiana de Criadores de Ganado Cebú† - ASOCEBU, has been leading a dairy milk control program which led to the creation
Daniela Ferro, Jhon Gil, Ariel Jiménez, Carlos Manrique, Carlos A. Martínez   +4 more
doaj   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

Identification and Expert Approach to Controlling the Cement Grinding Process Using Artificial Neural Networks and Other Non-Linear Models

IEEE Access
The paper involved conducting preliminary research to explore the identification and control of a multi-dimensional, non-linear, and non-stationary cement grinding process using artificial neural networks and various other non-linear models.
Dawid Pawus, Szczepan Paszkiel
doaj   +1 more source

Lagrangian formulation for noncommutative nonlinear systems

, 2011
In this work we use the well known formalism developed by Faddeev and Jackiw to introduce noncommutativity within two nonlinear systems, the SU(2) Skyrme and O(3) nonlinear sigma models.
A. C. R. MENDES, Abreu E. M. C., Abreu E. M. C., Adkins G., C. NEVES, Connes A., E. M. C. ABREU, Flato M., Horváthy P. A., J. ANANIAS NETO, M. V. MARCIAL, Minwalla S., Seiberg N., Seiberg N., W. OLIVEIRA   +14 more
core   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Multibody-Based Input and State Observers Using Adaptive Extended Kalman Filter

Sensors, 2021
The aim of this work is to explore the suitability of adaptive methods for state estimators based on multibody dynamics, which present severe non-linearities.
Antonio J. Rodríguez, Emilio Sanjurjo, Roland Pastorino, Miguel Á. Naya   +3 more
doaj   +1 more source

Generalized Nonlinear Yule Models [PDF]

Journal of Statistical Physics, 2016
With the aim of considering models with persistent memory we propose a fractional nonlinear modification of the classical Yule model often studied in the context of macrovolution. Here the model is analyzed and interpreted in the framework of the development of networks such as the World Wide Web.
Lansky, Petr, POLITO, Federico, SACERDOTE, Laura Lea   +2 more
openaire   +4 more sources