Results 51 to 60 of about 1,370,774 (268)

Nonlinear deterministic equations in biological evolution

, 2011
We review models of biological evolution in which the population frequency changes deterministically with time. If the population is self-replicating, although the equations for simple prototypes can be linearised, nonlinear equations arise in many ...
Baake E., Baake E., Boe L., Brumer Y., Bürger R., Crow J. F., Crow J. F., de Visser J. A. G. M., Drake J. W., Durrett R., Eigen M., Eigen M., Eshel I., Ewens W. J., Hartl D. L., Higgs P. G., Izmailian N. Sh., Jacobi M. N., Jain K., Jain K., Jain K., Jain K., Jones B., Kamp C., Kimura M., Komarova N. L., Kouyos R. D., LeClerc J. E., Nagar A., Nilsson M., Nilsson M., Nowak M. A., Nowak M. A., Nowak M. A., Otto S. P., Park S.-C., Perelson A. S., Quer J., Saakian D. B., Sardanyes J., Seetharaman S., Smith J. Maynard, Sniegowski P. D., Sorace A., Sturtevant A. H., Tannenbaum E., Thompson C. J., Wiehe T., Wiehe T., Wilke C. O., Woodcock G.   +50 more
core   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Applications of Artificial Intelligence in Water Resources Forecasting

EDIS
The advent of artificial intelligence (AI) and machine learning has permeated every aspect of our lives. Water resource management is becoming increasingly important due to the impacts of climate change and human activities.
Golmar Golmohammadi, Seyed Mostafa Biazar, Rohith Reddy Nedhunuri, Nikolaos Tziolas   +3 more
doaj   +1 more source

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

FEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang, Jing Wang, De‐Hui Qian, Yang‐Fan Lv, Tian‐Le Cheng, Da‐Peng Wang, Jing Zhang, Ye Fan   +7 more
wiley   +1 more source

GALACTIC NONLINEAR DYNAMIC MODEL [PDF]

International Journal of Modern Physics A, 2009
We develop a model for spiral galaxies based on a nonlinear realization of the Newtonian dynamics starting from the momentum and mass conservations in the phase space. The radial solution exhibits a rotation curve in qualitative accordance with the observational data.
De Melo, C. A. M., Resende, S. T.
openaire   +2 more sources

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Asset allocation and regime switching on Croatian financial market

Croatian Operational Research Review, 2016
It has been known for quite some time now that financial markets exhibit changes in regimes over time. A majority of the literature tends to support that financial markets undergo regimes of bull and bear markets. This characteristic should be modeled in
Tihana Škrinjarić, Boško Šego
doaj   +1 more source

Generalized height-diameter models for five pine species at Southern Mexico

Forest Science and Technology, 2020
Generalized height-diameter at breast height (D) models are essential for the estimation of the timber stocks of a forest stand, as well as in the generation of base information to develop forest growth models, and as basic inputs in the development of ...
Wenceslao Santiago-García, Antonio Heriberto Jacinto-Salinas, Gerardo Rodríguez-Ortiz, Adan Nava-Nava, Elías Santiago-García, Gregorio Ángeles-Pérez, José Raymundo Enríquez-del Valle   +6 more
doaj   +1 more source

Modelling nonlinear hydroelastic waves [PDF]

Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences, 2011
This paper uses the special Cosserat theory of hyperelastic shells satisfying Kirchoff’s hypothesis and irrotational flow theory to model the interaction between a heavy thin elastic sheet and an infinite ocean beneath it. From a general discussion of three-dimensional motions, involving an Eulerian description of the flow and a Lagrangian description ...
Plotnikov, P I, Toland, John F
openaire   +3 more sources

Nonlinear Models of Neural and Genetic Network Dynamics:\ud \ud Natural Transformations of Łukasiewicz Logic LM-Algebras in a Łukasiewicz-Topos as Representations of Neural Network Development and Neoplastic Transformations \ud [PDF]

, 2011
A categorical and Łukasiewicz-Topos framework for Algebraic Logic models of nonlinear dynamics in complex functional systems such as Neural Networks, Cell Genome and Interactome Networks is introduced.
Baianu, Professor I.C.
core