Results 61 to 70 of about 615,645 (274)

Optimal control strategies for a two-item production-maintenance system with deterioration

Results in Control and Optimization
In this work, the problem of optimal control for a two-item production-maintenance system with deterioration is considered. An inventory system process performance can be evaluated by analyzing the proportion of good units produced as the end product ...
S. Sowmica, M. Suvinthra
doaj   +1 more source

Practical stability of time‐varying positive systems with time delay

IET Control Theory & Applications, 2021
This paper considers the problem of practical stability for time‐varying positive systems with time delay. For both non‐linear time‐varying positive systems and linear time‐varying positive (LTVP) systems with time delay, sufficient conditions on ...
Ruonan Li, Ping Zhao
doaj   +1 more source

Feedback Stabilization Methods for the Numerical Solution of Systems of Ordinary Differential Equations [PDF]

, 2008
In this work we study the problem of step size selection for numerical schemes, which guarantees that the numerical solution presents the same qualitative behavior as the original system of ordinary differential equations, by means of tools from ...
Ch. Tsitouras, George Psihoyios, Iasson Karafyllis, Lars Grüne, Theodore E. Simos   +4 more
core   +3 more sources

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

RBF NN-Based Backstepping Adaptive Control for a Class of Nonlinear Systems

MATEC Web of Conferences, 2018
There are many control methods for nonlinear systems, but some of them can not control nonlinear mismatched systems very well. Backstepping control has obvious advantages in controlling nonlinear mismatched systems.
Zhao Haibo, Wang Chengguang
doaj   +1 more source

Molecular imaging predicts trastuzumab‐deruxtecan (T‐DXd) response in head and neck cancer xenograft models

Molecular Oncology, EarlyView.
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed, Lucas Mani, Muhammad Bilal Mirza, Ashtyn McAdoo, Takahito Kondo, Hidenori Tanaka, Nicole Meeks, Eben Rosenthal, Marisa Hom   +8 more
wiley   +1 more source

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

Molecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

Optimal control of nonlinear systems with input constraints using linear time varying approximations

Nonlinear Analysis, 2016
We propose a new method to solve input constrained optimal control problems for autonomous nonlinear systems affine in control. We then extend the method to compute the bang-bang control solutions under the symmetric control constraints.
Mehmet Itik
doaj   +1 more source

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

Molecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon, Moa Stenudd, Margherita Zamboni, Kanar Alkass, Carl‐Johan Eriksson, Lars Pedersen, Alrik Schörling, Anna Thoss, Anders Bergh, Pernilla Wikström, Hans‐Olov Adami, Henrik Toft Sørensen, Henrik Druid, Jonas Frisén   +13 more
wiley   +1 more source

Adaptive backstepping complementary sliding mode control with parameter estimation and dead‐zone modification for PMLSM servo system

IET Power Electronics, 2021
An adaptive backstepping complementary sliding mode control (ABCSMC) with dead‐zone parameter modification applicable to the permanent magnet linear synchronous motor is proposed in order to achieve high‐performance servo control fields.
Hongyan Jin, Ximei Zhao, Tianhe Wang
doaj   +1 more source