Results 51 to 60 of about 64,377 (317)
Optimal control strategies for a two-item production-maintenance system with deterioration
In this work, the problem of optimal control for a two-item production-maintenance system with deterioration is considered. An inventory system process performance can be evaluated by analyzing the proportion of good units produced as the end product ...
S. Sowmica, M. Suvinthra
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Practical stability of time‐varying positive systems with time delay
This paper considers the problem of practical stability for time‐varying positive systems with time delay. For both non‐linear time‐varying positive systems and linear time‐varying positive (LTVP) systems with time delay, sufficient conditions on ...
Ruonan Li, Ping Zhao
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Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Nonlinear control theory and chaotic dynamical systems [PDF]
The author treats the role of multiparameters in the existence of solutions of highly coupled nonlinear dynamical systems and numerical computation of solutions. An attempt is made to develop methods applicable to control of highly coupled nonlinear dynamical systems containing multiparameters which may have a chaotic behavior.
openaire +1 more source
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
An adaptive backstepping complementary sliding mode control (ABCSMC) with dead‐zone parameter modification applicable to the permanent magnet linear synchronous motor is proposed in order to achieve high‐performance servo control fields.
Hongyan Jin, Ximei Zhao, Tianhe Wang
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The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
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Finite-Time Incremental Passivity and Output Tracking Control for Switched Nonlinear Systems
This paper studies the finite-time incremental passivity of switched nonlinear systems. Then, the established theory is applied to solve the finite-time output tracking control problem of switched nonlinear systems.
Shuo Liu, Hongbo Pang
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It is a very important issue to minimise the change of the interconnect structure matrix when stabilising a port‐controlled Hamiltonian (PCH) system.
Tianyi Zhao, Guangren Duan
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The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source

