Results 71 to 80 of about 2,128,044 (322)
FEBS Open Bio, EarlyView.Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu +5 more
wiley +1 more source
Statistical Linearization Analysis of a Hydropneumatic Suspension System With Nonlinearity
IEEE Access, 2018 Hydropneumatic suspension has the characteristics of nonlinear stiffness, nonlinear friction damping, and nonlinear hydraulic damping, and therefore, it has been widely applied to heavy vehicles.
Zuti Zhang, Shuping Cao, Chunhong Ruan
doaj +1 more source
Control of wavepacket spreading in nonlinear finite disordered lattices
, 2008 In the absence of nonlinearity all normal modes (NMs) of a chain with disorder are spatially localized (Anderson localization). We study the action of nonlinearity, whose strength is ramped linearly in time. It leads to a spreading of a wavepacket due to
Rodrigo A. Vicencio, Sergej Flach
core +1 more source
Cavity-Free Optical Isolators and Circulators Using a Chiral Cross-Kerr Nonlinearity.
Physical Review Letters, 2018 Optical nonlinearity has been widely used to try to produce optical isolators. However, this is very difficult to achieve due to dynamical reciprocity.
K. Xia, F. Nori, Min Xiao
semanticscholar +1 more source
FEBS Open Bio, EarlyView.Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn +4 more
wiley +1 more source
Entropy, 2023 Several heart rate variability (HRV) characteristics of patients with myocardial ischemia are associated with a higher mortality risk. However, the immediate effect of acute ischemia on the HRV nonlinear dynamical behavior is unknown.
Martín Calderón-Juárez +3 more
doaj +1 more source
Forced nonlinear Schrödinger equation with arbitrary nonlinearity [PDF]
Physical Review E, 2012 37 pages, 20 ...
Cooper, Fred +4 more
openaire +5 more sources
FEBS Open Bio, EarlyView.This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake +4 more
wiley +1 more source
A Convergence Theorem for the Nonequilibrium States in the Discrete Thermostatted Kinetic Theory
Mathematics, 2019 The existence and reaching of nonequilibrium stationary states are important issues that need to be taken into account in the development of mathematical modeling frameworks for far off equilibrium complex systems.
Carlo Bianca, Marco Menale
doaj +1 more source
Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer
Aging and Cancer, EarlyView.Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss +12 more
wiley +1 more source